Fragmin and Melaena - a phase IV clinical study of FDA data

Summary:

Melaena is reported as a side effect among people who take Fragmin (dalteparin sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Plavix, and have High blood pressure.

The phase IV clinical study analyzes which people have Melaena when taking Fragmin. It is created by eHealthMe based on reports of 11,893 people who have side effects when taking Fragmin from the FDA, and is updated regularly.

What is Fragmin?

Fragmin has active ingredients of dalteparin sodium. It is often used in deep venous thrombosis. eHealthMe is studying from 11,999 Fragmin users. Check the latest studies of Fragmin.

What is Melaena?

Melaena (the passage of black, tarry stools) is found to be associated with 1,322 drugs and 1,475 conditions by eHealthMe. Check the latest studies of Melaena.

On Jul, 11, 2026

11,893 people reported to have side effects when taking Fragmin.
Among them, 82 people (0.69%) have Melaena.

Among these 82 people:

How long have people been on Fragmin when they have Melaena? *

What is the gender of people who have Melaena when taking Fragmin? *

female: 60.76 %
male: 39.24 %

What is the age of people who have Melaena when taking Fragmin? *

What are other drugs people take besides Fragmin? *

What are other side effects people have besides Melaena? *

Haematemesis (vomiting of blood): 20 people, 24.39%
Gastric Ulcer (stomach ulcer): 20 people, 24.39%
Haemorrhagic Anaemia (anaemia due to excessive bleeding): 17 people, 20.73%
Haemoglobin Decreased: 14 people, 17.07%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 14 people, 17.07%
Hypotension (abnormally low blood pressure): 12 people, 14.63%
Thrombocytopenia (decrease of platelets in blood): 8 people, 9.76%
Paleness (unusual lightness of skin colour): 7 people, 8.54%
Gastric Ulcer Haemorrhage (bleeding ulcer of stomach): 7 people, 8.54%
Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies): 7 people, 8.54%

What are the existing conditions these people have? *

High Blood Pressure: 10 people, 12.20%
Type 2 Diabetes: 7 people, 8.54%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 4.88%
Pneumonia: 4 people, 4.88%
Heart Attack: 3 people, 3.66%
Essential Hypertension (primary hypertension): 3 people, 3.66%
Pain: 3 people, 3.66%
Acute Myocardial Infarction (acute heart attack): 3 people, 3.66%
Angina Unstable (chest pain due to ischemia of the heart muscle- unstable): 3 people, 3.66%
Diabetes: 2 people, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Fragmin and have Melaena?

- Check whether Melaena is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Fragmin:

Fragmin (11,999 reports)

Melaena treatments and more:

Melaena (29,850 reports)

Browse all side effects of Fragmin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Melaena:

Melaena (1,322 drugs)

Browse all the conditions that are associated with Melaena:

Melaena (1,475 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on dalteparin sodium (the active ingredients of Fragmin) and Fragmin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.