Frova and Joint pain - a phase IV clinical study of FDA data

Summary:

Joint pain is reported as a side effect among people who take Frova (frovatriptan succinate), especially for people who are female, 50-59 old, have been taking the drug for 1 - 2 years also take Vitamin D3, and have Crohn's disease.

The phase IV clinical study analyzes which people have Joint pain when taking Frova. It is created by eHealthMe based on reports of 1,941 people who have side effects when taking Frova from the FDA, and is updated regularly.

What is Frova?

Frova has active ingredients of frovatriptan succinate. It is often used in migraine. eHealthMe is studying from 2,100 Frova users. Check the latest studies of Frova.

What is Joint pain?

Joint pain is found to be associated with 3,328 drugs and 5,212 conditions by eHealthMe. Check the latest studies of Joint pain.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

1,941 people reported to have side effects when taking Frova.
Among them, 78 people (4.02%) have Joint pain.

Among these 78 people:

How long have people been on Frova when they have Joint pain? *

What is the gender of people who have Joint pain when taking Frova? *

female: 95.45 %
male: 4.55 %

What is the age of people who have Joint pain when taking Frova? *

What are other drugs people take besides Frova? *

What are other side effects people have besides Joint pain? *

Headache (pain in head): 28 people, 35.90%
Nausea (feeling of having an urge to vomit): 27 people, 34.62%
High Blood Pressure: 26 people, 33.33%
Pain: 26 people, 33.33%
Fatigue (feeling of tiredness): 19 people, 24.36%
Chest Pain: 18 people, 23.08%
Joint Swelling: 18 people, 23.08%
Nausea And Vomiting: 17 people, 21.79%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 17 people, 21.79%
Hair Loss: 16 people, 20.51%

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 16 people, 20.51%
Immunodeficiency Common Variable: 11 people, 14.10%
Pain: 8 people, 10.26%
Hair Loss: 6 people, 7.69%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 6.41%
Stress And Anxiety: 3 people, 3.85%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 3.85%
Headache (pain in head): 3 people, 3.85%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 3.85%
Depression: 2 people, 2.56%

* Approximation only. Some reports may have incomplete information.

Do you take Frova and have Joint pain?

- Check whether Joint pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Frova:

Frova (2,100 reports)

Joint pain treatments and more:

Joint pain (542,935 reports)

Browse all side effects of Frova:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint pain:

Joint pain (3,328 drugs)

Browse all the conditions that are associated with Joint pain:

Joint pain (5,212 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on frovatriptan succinate (the active ingredients of Frova) and Frova (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.