Gabapentin and Retinal dystrophy - a phase IV clinical study of FDA data

Summary:

Retinal dystrophy is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years also take Elmiron, and have Cystitis interstitial.

The phase IV clinical study analyzes which people have Retinal dystrophy when taking Gabapentin. It is created by eHealthMe based on reports of 313,421 people who have side effects when taking Gabapentin from the FDA, and is updated regularly.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,983 Gabapentin users. Check the latest studies of Gabapentin.

What is Retinal dystrophy?

Retinal dystrophy (progressive weakness and wasting of the retina) is found to be associated with 36 drugs and 44 conditions by eHealthMe. Check the latest studies of Retinal dystrophy.



On Jul, 12, 2026

313,421 people reported to have side effects when taking Gabapentin.
Among them, 23 people (0.01%) have Retinal dystrophy.

Could Gabapentin cause Retinal dystrophy?

Among these 23 people:

How long have people been on Gabapentin when they have Retinal dystrophy? *

  • < 1 month: 28.57 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 57.14 %
  • 10+ years: 14.29 %

What is the gender of people who have Retinal dystrophy when taking Gabapentin? *

  • female: 100 %
  • male: 0.0 %

What is the age of people who have Retinal dystrophy when taking Gabapentin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 4.35 %
  • 30-39: 21.74 %
  • 40-49: 13.04 %
  • 50-59: 34.78 %
  • 60+: 26.09 %

What are other drugs people take besides Gabapentin? *

  1. Elmiron: 20 people, 86.96%
  2. Estradiol: 7 people, 30.43%
  3. Omeprazole: 6 people, 26.09%
  4. Hydroxyzine: 5 people, 21.74%
  5. Tramadol: 4 people, 17.39%
  6. Paroxetine: 4 people, 17.39%
  7. Oxybutynin: 4 people, 17.39%
  8. Methylprednisolone: 4 people, 17.39%
  9. Zofran: 4 people, 17.39%
  10. Promethazine: 4 people, 17.39%

What are other side effects people have besides Retinal dystrophy? *

  1. Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest): 6 people, 26.09%
  2. Macular Degeneration (painless eye condition that leads to the gradual loss of central vision): 5 people, 21.74%
  3. Nausea (feeling of having an urge to vomit): 3 people, 13.04%
  4. Ocular Discomfort (a generic expression when there is lack of ease in/about the eyes): 3 people, 13.04%
  5. Fever: 3 people, 13.04%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 13.04%
  7. Neuritis (inflammation of nerve): 3 people, 13.04%
  8. Body Temperature Increased: 3 people, 13.04%
  9. Retinal Pigmentation (pigmentation of retina): 3 people, 13.04%
  10. Feeling Abnormal: 3 people, 13.04%

What are the existing conditions these people have? *

  1. Cystitis Interstitial (unknown cause characterized by bladder pain): 20 people, 86.96%
  2. Depression: 12 people, 52.17%
  3. Stress And Anxiety: 8 people, 34.78%
  4. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 6 people, 26.09%
  5. Asthma: 6 people, 26.09%
  6. High Blood Cholesterol: 6 people, 26.09%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 21.74%
  8. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 5 people, 21.74%
  9. Sleep Disorder: 5 people, 21.74%
  10. Bipolar Disorder (mood disorder): 5 people, 21.74%

* Approximation only. Some reports may have incomplete information.

Do you take Gabapentin and have Retinal dystrophy?

- Check whether Retinal dystrophy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gabapentin:

Retinal dystrophy treatments and more:

How severe was Retinal dystrophy and when was it recovered:

Expand to all the drugs that have ingredients of gabapentin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gabapentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Retinal dystrophy:

Browse all the conditions that are associated with Retinal dystrophy:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on gabapentin (the active ingredients of Gabapentin) and Gabapentin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: