Gemfibrozil and Aortic valve sclerosis - a phase IV clinical study of FDA data

Summary:

Aortic valve sclerosis is reported as a side effect among people who take Gemfibrozil (gemfibrozil), especially for people who are male, 60+ old, also take Simvastatin, and have High blood pressure.

The phase IV clinical study analyzes which people have Aortic valve sclerosis when taking Gemfibrozil. It is created by eHealthMe based on reports of 17,763 people who have side effects when taking Gemfibrozil from the FDA, and is updated regularly.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

What is Aortic valve sclerosis?

Aortic valve sclerosis (narrowing of the aortic valve) is found to be associated with 367 drugs and 435 conditions by eHealthMe. Check the latest studies of Aortic valve sclerosis.



On Jul, 14, 2026

17,763 people reported to have side effects when taking Gemfibrozil.
Among them, 12 people (0.07%) have Aortic valve sclerosis.

Could Gemfibrozil cause Aortic valve sclerosis?

Among these 12 people:

What is the gender of people who have Aortic valve sclerosis when taking Gemfibrozil? *

  • female: 25 %
  • male: 75 %

What is the age of people who have Aortic valve sclerosis when taking Gemfibrozil? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 45.45 %
  • 60+: 54.55 %

What are other drugs people take besides Gemfibrozil? *

  1. Lisinopril: 4 people, 33.33%
  2. Digoxin: 4 people, 33.33%
  3. Simvastatin: 4 people, 33.33%
  4. Metformin: 3 people, 25.00%
  5. Fish Oil: 3 people, 25.00%
  6. Glipizide: 3 people, 25.00%
  7. Hydrochlorothiazide: 3 people, 25.00%
  8. Niacin: 3 people, 25.00%
  9. Nitroglycerin: 3 people, 25.00%
  10. Lorazepam: 3 people, 25.00%

What are other side effects people have besides Aortic valve sclerosis? *

  1. Mitral Valve Incompetence (inefficient heart valve): 10 people, 83.33%
  2. Tricuspid Valve Incompetence (inefficient heart valve): 10 people, 83.33%
  3. Weakness: 5 people, 41.67%
  4. Dizziness: 5 people, 41.67%
  5. Cardiomyopathy (weakening of the heart muscle): 4 people, 33.33%
  6. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 4 people, 33.33%
  7. Aortic Valve Incompetence: 4 people, 33.33%
  8. Arrhythmias (irregular heartbeat): 4 people, 33.33%
  9. Dyspnea (difficult or laboured breathing): 4 people, 33.33%
  10. Electrocardiogram T Wave Abnormal: 4 people, 33.33%

What are the existing conditions these people have? *

  1. High Blood Pressure: 2 people, 16.67%
  2. Seborrhoeic Dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp): 1 person, 8.33%
  3. Seasonal Allergy (allergic condition due to certain season): 1 person, 8.33%
  4. Blood Triglycerides Decreased: 1 person, 8.33%
  5. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 8.33%
  6. Diabetes: 1 person, 8.33%
  7. Diarrhea: 1 person, 8.33%
  8. Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 8.33%
  9. Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 8.33%
  10. Insulin-Requiring Type Ii Diabetes Mellitus: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Gemfibrozil and have Aortic valve sclerosis?

- Check whether Aortic valve sclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gemfibrozil:

Aortic valve sclerosis treatments and more:

How severe was Aortic valve sclerosis and when was it recovered:

Expand to all the drugs that have ingredients of gemfibrozil:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gemfibrozil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic valve sclerosis:

Browse all the conditions that are associated with Aortic valve sclerosis:


How the study uses the data?

The study uses data from the FDA. It is based on gemfibrozil (the active ingredients of Gemfibrozil) and Gemfibrozil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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