Gemfibrozil and Hepatic enzyme increased - a phase IV clinical study of FDA data

Summary:

Hepatic enzyme increased is reported as a side effect among people who take Gemfibrozil (gemfibrozil), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Simvastatin, and have Hyperlipidaemia.

The phase IV clinical study analyzes which people have Hepatic enzyme increased when taking Gemfibrozil. It is created by eHealthMe based on reports of 17,763 people who have side effects when taking Gemfibrozil from the FDA, and is updated regularly.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

What is Hepatic enzyme increased?

Hepatic enzyme increased is found to be associated with 1,884 drugs and 2,016 conditions by eHealthMe. Check the latest studies of Hepatic enzyme increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

17,763 people reported to have side effects when taking Gemfibrozil.
Among them, 92 people (0.52%) have Hepatic enzyme increased.

Could Gemfibrozil cause Hepatic enzyme increased?

Among these 92 people:

How long have people been on Gemfibrozil when they have Hepatic enzyme increased? *

What is the gender of people who have Hepatic enzyme increased when taking Gemfibrozil? *

female: 40.7 %
male: 59.3 %

What is the age of people who have Hepatic enzyme increased when taking Gemfibrozil? *

What are other drugs people take besides Gemfibrozil? *

What are other side effects people have besides Hepatic enzyme increased? *

Fatigue (feeling of tiredness): 15 people, 16.30%
Hepatic Steatosis (fatty liver disease): 14 people, 15.22%
Blood Creatine Phosphokinase Increased: 11 people, 11.96%
Weakness: 11 people, 11.96%
Diarrhea: 11 people, 11.96%
Constipation: 11 people, 11.96%
Muscle Aches (muscle pain): 10 people, 10.87%
Fall: 9 people, 9.78%
Nausea (feeling of having an urge to vomit): 8 people, 8.70%
Hair Loss: 8 people, 8.70%

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 18 people, 19.57%
High Blood Pressure: 7 people, 7.61%
Psoriasis (immune-mediated disease that affects the skin): 6 people, 6.52%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 4.35%
Bipolar Disorder (mood disorder): 4 people, 4.35%
Pain: 4 people, 4.35%
Diabetes: 4 people, 4.35%
Osteoporosis (bones weak and more likely to break): 3 people, 3.26%
Glaucoma (increased fluid pressure in the eye with vision loss): 3 people, 3.26%
Lipids Increased (excess lipid in body): 3 people, 3.26%

* Approximation only. Some reports may have incomplete information.

Do you take Gemfibrozil and have Hepatic enzyme increased?

- Check whether Hepatic enzyme increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gemfibrozil:

Gemfibrozil (18,213 reports)

Browse all side effects of Gemfibrozil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatic enzyme increased:

Hepatic enzyme increased (1,884 drugs)

Browse all the conditions that are associated with Hepatic enzyme increased:

Hepatic enzyme increased (2,016 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on gemfibrozil (the active ingredients of Gemfibrozil) and Gemfibrozil (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.