Generlac and Pain - a phase IV clinical study of FDA data

Summary:

Pain is reported as a side effect among people who take Generlac (lactulose), especially for people who are female, 60+ old, also take Oxycodone, and have Hiv infection.

The phase IV clinical study analyzes which people have Pain when taking Generlac. It is created by eHealthMe based on reports of 642 people who have side effects when taking Generlac from the FDA, and is updated regularly.

What is Generlac?

Generlac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 657 Generlac users. Check the latest studies of Generlac.

What is Pain?

Pain is found to be associated with 3,819 drugs and 5,856 conditions by eHealthMe. Check the latest studies of Pain.



On Apr, 30, 2026

642 people reported to have side effects when taking Generlac.
Among them, 34 people (5.3%) have Pain.

Could Generlac cause Pain?

Among these 34 people:

What is the gender of people who have Pain when taking Generlac? *

  • female: 64.71 %
  • male: 35.29 %

What is the age of people who have Pain when taking Generlac? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 3.85 %
  • 40-49: 38.46 %
  • 50-59: 11.54 %
  • 60+: 46.15 %

What are other drugs people take besides Generlac? *

  1. Oxycodone: 10 people, 29.41%
  2. Temazepam: 8 people, 23.53%
  3. Furosemide: 7 people, 20.59%
  4. Spiriva: 7 people, 20.59%
  5. Xifaxan: 7 people, 20.59%
  6. Ventolin Hfa: 6 people, 17.65%
  7. Truvada: 6 people, 17.65%
  8. Stribild: 6 people, 17.65%
  9. Metformin: 6 people, 17.65%
  10. Vitamin D3: 6 people, 17.65%

What are other side effects people have besides Pain? *

  1. Fatigue (feeling of tiredness): 8 people, 23.53%
  2. Stress And Anxiety: 8 people, 23.53%
  3. Emotional Distress: 7 people, 20.59%
  4. Anhedonia (inability to experience pleasure from activities usually found enjoyable): 6 people, 17.65%
  5. Bone Density Decreased: 6 people, 17.65%
  6. Weight Decreased: 5 people, 14.71%
  7. Multiple Fractures: 5 people, 14.71%
  8. Renal Disorder (kidney disease): 5 people, 14.71%
  9. Osteoporosis (bones weak and more likely to break): 5 people, 14.71%
  10. Pain In Extremity: 5 people, 14.71%

What are the existing conditions these people have? *

  1. Hiv Infection: 6 people, 17.65%
  2. Hypersensitivity: 4 people, 11.76%
  3. Asthma: 3 people, 8.82%
  4. Multiple Myeloma (cancer of the plasma cells): 3 people, 8.82%
  5. Hepatitis C: 3 people, 8.82%
  6. Quit Smoking: 3 people, 8.82%
  7. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 5.88%
  8. Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 2 people, 5.88%
  9. Hepatocellular Carcinoma (liver cancer): 2 people, 5.88%
  10. Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Generlac and have Pain?

- Check whether Pain is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Generlac:

Pain treatments and more:

  • Pain (1,140,593 reports)

How severe was Pain and when was it recovered:

Expand to all the drugs that have ingredients of lactulose:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Generlac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pain:

  • Pain (3,819 drugs)

Browse all the conditions that are associated with Pain:

  • Pain (5,856 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lactulose (the active ingredients of Generlac) and Generlac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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