Genotropin and Aseptic necrosis - a phase IV clinical study of FDA data

Summary:

Aseptic necrosis is reported as a side effect among people who take Genotropin (somatropin recombinant), especially for people who are male, 10-19 old, have been taking the drug for 2 - 5 years also take Synthroid, and have Hypopituitarism.

The phase IV clinical study analyzes which people have Aseptic necrosis when taking Genotropin. It is created by eHealthMe based on reports of 41,867 people who have side effects when taking Genotropin from the FDA, and is updated regularly.

What is Genotropin?

Genotropin has active ingredients of somatropin recombinant. It is often used in growth hormone deficiency. eHealthMe is studying from 41,924 Genotropin users. Check the latest studies of Genotropin.

What is Aseptic necrosis?

Aseptic necrosis (the death of bone tissue due to a lack of blood supply) is found to be associated with 1,347 drugs and 1,692 conditions by eHealthMe. Check the latest studies of Aseptic necrosis.



On Jul, 13, 2026

41,867 people reported to have side effects when taking Genotropin.
Among them, 47 people (0.11%) have Aseptic necrosis.

Could Genotropin cause Aseptic necrosis?

Among these 47 people:

How long have people been on Genotropin when they have Aseptic necrosis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 17.65 %
  • 6 - 12 months: 11.76 %
  • 1 - 2 years: 5.88 %
  • 2 - 5 years: 41.18 %
  • 5 - 10 years: 5.88 %
  • 10+ years: 17.65 %

What is the gender of people who have Aseptic necrosis when taking Genotropin? *

  • female: 15.56 %
  • male: 84.44 %

What is the age of people who have Aseptic necrosis when taking Genotropin? *

  • 0-1: 0.0 %
  • 2-9: 12 %
  • 10-19: 60 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 28 %

What are other drugs people take besides Genotropin? *

  1. Synthroid: 26 people, 55.32%
  2. Magnesium Glycinate: 22 people, 46.81%
  3. Olmetec: 21 people, 44.68%
  4. Metformin: 21 people, 44.68%
  5. Glumetza: 21 people, 44.68%
  6. Vitamin B12: 19 people, 40.43%
  7. Calcium: 17 people, 36.17%
  8. Xylocaine: 16 people, 34.04%
  9. Ubidecarenone: 15 people, 31.91%
  10. Acetylsalicylic Acid: 10 people, 21.28%

What are other side effects people have besides Aseptic necrosis? *

  1. Pain: 21 people, 44.68%
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 18 people, 38.30%
  3. Chronic Kidney Disease: 18 people, 38.30%
  4. Coronary Heart Disease (narrowing or blockage of the coronary arteries): 18 people, 38.30%
  5. Bone Disorder: 17 people, 36.17%
  6. Tendonitis (a condition that causes pain and swelling of tendons): 16 people, 34.04%
  7. Cardiac Disorder: 16 people, 34.04%
  8. Weakness: 16 people, 34.04%
  9. Hypersensitivity: 13 people, 27.66%
  10. Fatigue (feeling of tiredness): 6 people, 12.77%

What are the existing conditions these people have? *

  1. Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 30 people, 63.83%
  2. Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 17 people, 36.17%
  3. Itching: 17 people, 36.17%
  4. Secondary Adrenocortical Insufficiency (inadequate secretion of acth by the pituitary gland): 16 people, 34.04%
  5. Pain: 16 people, 34.04%
  6. Wound: 16 people, 34.04%
  7. Tendonitis (a condition that causes pain and swelling of tendons): 16 people, 34.04%
  8. Nodule (a growth of abnormal tissue): 16 people, 34.04%
  9. Body Height Below Normal: 7 people, 14.89%
  10. Small For Dates Baby (an unborn baby is growing more slowly and is smaller than most babies are at the same age): 3 people, 6.38%

* Approximation only. Some reports may have incomplete information.

Do you take Genotropin and have Aseptic necrosis?

- Check whether Aseptic necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Genotropin:

Aseptic necrosis treatments and more:

How severe was Aseptic necrosis and when was it recovered:

Expand to all the drugs that have ingredients of somatropin recombinant:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Genotropin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aseptic necrosis:

Browse all the conditions that are associated with Aseptic necrosis:


How the study uses the data?

The study uses data from the FDA. It is based on somatropin recombinant (the active ingredients of Genotropin) and Genotropin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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