Gentamicin and Tumor lysis syndrome - a phase IV clinical study of FDA data

Summary:

Tumor lysis syndrome is reported as a side effect among people who take Gentamicin (gentamicin sulfate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Allopurinol, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Tumor lysis syndrome when taking Gentamicin. It is created by eHealthMe based on reports of 21,523 people who have side effects when taking Gentamicin from the FDA, and is updated regularly.

What is Gentamicin?

Gentamicin has active ingredients of gentamicin sulfate. It is often used in urinary tract infection. eHealthMe is studying from 21,654 Gentamicin users. Check the latest studies of Gentamicin.

What is Tumor lysis syndrome?

Tumor lysis syndrome is found to be associated with 618 drugs and 828 conditions by eHealthMe. Check the latest studies of Tumor lysis syndrome.



On May, 03, 2026

21,523 people reported to have side effects when taking Gentamicin.
Among them, 14 people (0.07%) have Tumor lysis syndrome.

Could Gentamicin cause Tumor lysis syndrome?

Among these 14 people:

How long have people been on Gentamicin when they have Tumor lysis syndrome? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Tumor lysis syndrome when taking Gentamicin? *

  • female: 28.57 %
  • male: 71.43 %

What is the age of people who have Tumor lysis syndrome when taking Gentamicin? *

  • 0-1: 0.0 %
  • 2-9: 16.67 %
  • 10-19: 8.33 %
  • 20-29: 0.0 %
  • 30-39: 8.33 %
  • 40-49: 0.0 %
  • 50-59: 8.33 %
  • 60+: 58.33 %

What are other drugs people take besides Gentamicin? *

  1. Prednisone: 6 people, 42.86%
  2. Allopurinol: 6 people, 42.86%
  3. Bactrim: 5 people, 35.71%
  4. Acetaminophen: 4 people, 28.57%
  5. Fluconazole: 4 people, 28.57%
  6. Folic Acid: 4 people, 28.57%
  7. Furosemide: 4 people, 28.57%
  8. Acyclovir: 4 people, 28.57%
  9. Methotrexate: 4 people, 28.57%
  10. Kayexalate: 3 people, 21.43%

What are other side effects people have besides Tumor lysis syndrome? *

  1. Hypocalcaemia (levels of calcium in blood serum are abnormally low): 5 people, 35.71%
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 5 people, 35.71%
  3. Hyperkalemia (damage to or disease of the kidney): 5 people, 35.71%
  4. Abdominal Pain: 4 people, 28.57%
  5. Acute Kidney Failure: 4 people, 28.57%
  6. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 4 people, 28.57%
  7. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 3 people, 21.43%
  8. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 3 people, 21.43%
  9. Sepsis (a severe blood infection that can lead to organ failure and death): 3 people, 21.43%
  10. Weight Decreased: 3 people, 21.43%

What are the existing conditions these people have? *

  1. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 4 people, 28.57%
  2. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 3 people, 21.43%
  3. Pain: 3 people, 21.43%
  4. Nausea (feeling of having an urge to vomit): 3 people, 21.43%
  5. Insomnia (sleeplessness): 3 people, 21.43%
  6. Hyperkalemia (damage to or disease of the kidney): 3 people, 21.43%
  7. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 14.29%
  8. Streptococcal Infection: 2 people, 14.29%
  9. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 14.29%
  10. Dyslipidaemia (abnormal amount of lipids): 2 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Gentamicin and have Tumor lysis syndrome?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gentamicin:

Tumor lysis syndrome treatments and more:

How severe was Tumor lysis syndrome and when was it recovered:

Expand to all the drugs that have ingredients of gentamicin sulfate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gentamicin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tumor lysis syndrome:

Browse all the conditions that are associated with Tumor lysis syndrome:


How the study uses the data?

The study uses data from the FDA. It is based on gentamicin sulfate (the active ingredients of Gentamicin) and Gentamicin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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