Geodon and Flat affect - a phase IV clinical study of FDA data

Summary:

Flat affect is reported as a side effect among people who take Geodon (ziprasidone hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 1 - 6 months also take Zyprexa, and have Hallucinations.

The phase IV clinical study analyzes which people have Flat affect when taking Geodon. It is created by eHealthMe based on reports of 18,215 people who have side effects when taking Geodon from the FDA, and is updated regularly.

What is Geodon?

Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,504 Geodon users. Check the latest studies of Geodon.

What is Flat affect?

Flat affect (absence of emotional response to a situation) is found to be associated with 295 drugs and 458 conditions by eHealthMe. Check the latest studies of Flat affect.

On Feb, 15, 2026

18,215 people reported to have side effects when taking Geodon.
Among them, 38 people (0.21%) have Flat affect.

Among these 38 people:

How long have people been on Geodon when they have Flat affect? *

What is the gender of people who have Flat affect when taking Geodon? *

female: 73.68 %
male: 26.32 %

What is the age of people who have Flat affect when taking Geodon? *

What are other drugs people take besides Geodon? *

Zyprexa: 16 people, 42.11%
Cogentin: 12 people, 31.58%
Celexa: 11 people, 28.95%
Depakote: 11 people, 28.95%
Buspar: 6 people, 15.79%
Prozac: 6 people, 15.79%
Wellbutrin: 6 people, 15.79%
Paxil: 6 people, 15.79%
Lorazepam: 6 people, 15.79%
Paroxetine Hydrochloride: 5 people, 13.16%

What are other side effects people have besides Flat affect? *

Weight Increased: 18 people, 47.37%
Insomnia (sleeplessness): 17 people, 44.74%
Feeling Abnormal: 17 people, 44.74%
Nightmares (unpleasant dreams): 14 people, 36.84%
Arrhythmias (irregular heartbeat): 13 people, 34.21%
Loss Of Consciousness: 13 people, 34.21%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 13 people, 34.21%
Memory Loss: 13 people, 34.21%
Sinus Bradycardia (an unusually slow heartbeat due to heart disease): 12 people, 31.58%
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down): 12 people, 31.58%

What are the existing conditions these people have? *

Hallucinations (sensations that appear real but are created by your mind): 10 people, 26.32%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 6 people, 15.79%
Tuberculosis Skin Test Positive: 4 people, 10.53%
Sleep Disorder: 2 people, 5.26%
Affective Disorder (mental disorder): 2 people, 5.26%
Ill-Defined Disorder: 2 people, 5.26%
Stress And Anxiety: 2 people, 5.26%
Insomnia (sleeplessness): 1 person, 2.63%
Adjustment Disorder With Depressed Mood: 1 person, 2.63%
Depressed Mood: 1 person, 2.63%

* Approximation only. Some reports may have incomplete information.

Do you take Geodon and have Flat affect?

- Check whether Flat affect is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Geodon:

Geodon (19,504 reports)

Flat affect treatments and more:

Flat affect (2,784 reports)

Browse all side effects of Geodon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Flat affect:

Flat affect (295 drugs)

Browse all the conditions that are associated with Flat affect:

Flat affect (458 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ziprasidone hydrochloride (the active ingredients of Geodon) and Geodon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.