Geodon and Mitral valve prolapse - a phase IV clinical study of FDA data

Summary:

Mitral valve prolapse is reported as a side effect among people who take Geodon (ziprasidone hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Lorazepam, and have Agitation.

The phase IV clinical study analyzes which people have Mitral valve prolapse when taking Geodon. It is created by eHealthMe based on reports of 18,215 people who have side effects when taking Geodon from the FDA, and is updated regularly.

What is Geodon?

Geodon has active ingredients of ziprasidone hydrochloride. It is often used in bipolar disorder. eHealthMe is studying from 19,505 Geodon users. Check the latest studies of Geodon.

What is Mitral valve prolapse?

Mitral valve prolapse (heart's mitral valve doesn't work well) is found to be associated with 504 drugs and 859 conditions by eHealthMe. Check the latest studies of Mitral valve prolapse.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 06, 2026

18,215 people reported to have side effects when taking Geodon.
Among them, 11 people (0.06%) have Mitral valve prolapse.

Could Geodon cause Mitral valve prolapse?

Among these 11 people:

How long have people been on Geodon when they have Mitral valve prolapse? *

What is the gender of people who have Mitral valve prolapse when taking Geodon? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Mitral valve prolapse when taking Geodon? *

What are other drugs people take besides Geodon? *

What are other side effects people have besides Mitral valve prolapse? *

Weight Increased: 3 people, 27.27%
Ventricular Hypertrophy (enlargement of ventricles (lower chambers) in the heart): 3 people, 27.27%
Gallstones (stone formation by bile component): 2 people, 18.18%
Social Fear (fear of interaction with other): 2 people, 18.18%
Pneumonia Aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree): 2 people, 18.18%
Cardio-Respiratory Arrest (sudden dysfunction of heart and lungs): 2 people, 18.18%
Inflammation: 2 people, 18.18%
Renal Disorder (kidney disease): 2 people, 18.18%
Disturbance In Attention: 2 people, 18.18%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 18.18%

What are the existing conditions these people have? *

Agitation (state of anxiety or nervous excitement): 4 people, 36.36%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 27.27%
Psychotic Disorder: 2 people, 18.18%
Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 1 person, 9.09%
Anger: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Geodon and have Mitral valve prolapse?

- Check whether Mitral valve prolapse is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Geodon:

Geodon (19,505 reports)

Browse all side effects of Geodon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Mitral valve prolapse:

Mitral valve prolapse (504 drugs)

Browse all the conditions that are associated with Mitral valve prolapse:

Mitral valve prolapse (859 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ziprasidone hydrochloride (the active ingredients of Geodon) and Geodon (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.