Gilotrif and Cheilitis - a phase IV clinical study of FDA data

Summary:

Cheilitis is reported as a side effect among people who take Gilotrif (afatinib dimaleate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Multivitamin, and have Lung adenocarcinoma.

The phase IV clinical study analyzes which people have Cheilitis when taking Gilotrif. It is created by eHealthMe based on reports of 6,046 people who have side effects when taking Gilotrif from the FDA, and is updated regularly.

What is Gilotrif?

Gilotrif has active ingredients of afatinib dimaleate. eHealthMe is studying from 6,055 Gilotrif users. Check the latest studies of Gilotrif.

What is Cheilitis?

Cheilitis (infection of lips) is found to be associated with 545 drugs and 910 conditions by eHealthMe. Check the latest studies of Cheilitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

6,046 people reported to have side effects when taking Gilotrif.
Among them, 32 people (0.53%) have Cheilitis.

Among these 32 people:

How long have people been on Gilotrif when they have Cheilitis? *

What is the gender of people who have Cheilitis when taking Gilotrif? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Cheilitis when taking Gilotrif? *

What are other drugs people take besides Gilotrif? *

What are other side effects people have besides Cheilitis? *

Diarrhea: 29 people, 90.62%
Stomatitis (inflammation of mucous membrane of mouth): 17 people, 53.12%
Rashes (redness): 14 people, 43.75%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 13 people, 40.62%
Nausea (feeling of having an urge to vomit): 12 people, 37.50%
Malignant Neoplasm Progression (cancer tumour came back): 8 people, 25.00%
Itching: 8 people, 25.00%
Paronychia (infection in the tissues adjacent to a nail on a finger or toe): 7 people, 21.88%
Nausea And Vomiting: 6 people, 18.75%
Cough: 5 people, 15.62%

What are the existing conditions these people have? *

Lung Adenocarcinoma (a form of non-small cell lung cancer): 17 people, 53.12%
Lung Cancer - Non-Small Cell (lung cancer): 11 people, 34.38%
High Blood Pressure: 4 people, 12.50%
Diarrhea: 3 people, 9.38%
Pain: 3 people, 9.38%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 6.25%
Diabetes: 2 people, 6.25%
Glaucoma (increased fluid pressure in the eye with vision loss): 2 people, 6.25%
Venous Thrombosis Limb (blood clot that forms in a vein in the limb): 2 people, 6.25%
Skin Disorder (skin disease): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Gilotrif and have Cheilitis?

- Check whether Cheilitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gilotrif:

Gilotrif (6,055 reports)

Cheilitis treatments and more:

Cheilitis (6,997 reports)

Browse all side effects of Gilotrif:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cheilitis:

Cheilitis (545 drugs)

Browse all the conditions that are associated with Cheilitis:

Cheilitis (910 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on afatinib dimaleate (the active ingredients of Gilotrif) and Gilotrif (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.