Gilotrif and Thrombocytopenia - a phase IV clinical study of FDA data

Summary:

Thrombocytopenia is reported as a side effect among people who take Gilotrif (afatinib dimaleate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Tagrisso, and have Lung cancer - non-small cell.

The phase IV clinical study analyzes which people have Thrombocytopenia when taking Gilotrif. It is created by eHealthMe based on reports of 6,046 people who have side effects when taking Gilotrif from the FDA, and is updated regularly.

What is Gilotrif?

Gilotrif has active ingredients of afatinib dimaleate. eHealthMe is studying from 6,055 Gilotrif users. Check the latest studies of Gilotrif.

What is Thrombocytopenia?

Thrombocytopenia (decrease of platelets in blood) is found to be associated with 2,791 drugs and 4,870 conditions by eHealthMe. Check the latest studies of Thrombocytopenia.

On Jul, 20, 2026

6,046 people reported to have side effects when taking Gilotrif.
Among them, 33 people (0.55%) have Thrombocytopenia.

Among these 33 people:

How long have people been on Gilotrif when they have Thrombocytopenia? *

What is the gender of people who have Thrombocytopenia when taking Gilotrif? *

female: 67.86 %
male: 32.14 %

What is the age of people who have Thrombocytopenia when taking Gilotrif? *

What are other drugs people take besides Gilotrif? *

Nexium: 4 people, 12.12%
Tagrisso: 4 people, 12.12%
Fexofenadine Hydrochloride: 2 people, 6.06%
Lyrica: 2 people, 6.06%
Losartan Potassium: 2 people, 6.06%
Paclitaxel: 2 people, 6.06%
Magnesium Oxide: 2 people, 6.06%
Carboplatin: 2 people, 6.06%
Amlodipine: 2 people, 6.06%
Alimta: 2 people, 6.06%

What are other side effects people have besides Thrombocytopenia? *

Diarrhea: 16 people, 48.48%
Rashes (redness): 9 people, 27.27%
Malignant Neoplasm Progression (cancer tumour came back): 8 people, 24.24%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 7 people, 21.21%
Anaemia (lack of blood): 6 people, 18.18%
Stomatitis (inflammation of mucous membrane of mouth): 6 people, 18.18%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 5 people, 15.15%
Hepatic Function Abnormal: 4 people, 12.12%
Constipation: 4 people, 12.12%
White Blood Cell Count Decreased: 3 people, 9.09%

What are the existing conditions these people have? *

Lung Cancer - Non-Small Cell (lung cancer): 12 people, 36.36%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 10 people, 30.30%
High Blood Pressure: 7 people, 21.21%
Rashes (redness): 5 people, 15.15%
High Blood Cholesterol: 3 people, 9.09%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 2 people, 6.06%
Lung Adenocarcinoma Stage Iv (the cancer has spread to other organs of the body, such as the other lung, brain, or liver): 2 people, 6.06%
Enlarged Prostate: 2 people, 6.06%
Diarrhea: 2 people, 6.06%
Joint Pain: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Gilotrif and have Thrombocytopenia?

- Check whether Thrombocytopenia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gilotrif:

Gilotrif (6,055 reports)

Thrombocytopenia treatments and more:

Thrombocytopenia (285,083 reports)

Browse all side effects of Gilotrif:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Thrombocytopenia:

Thrombocytopenia (2,791 drugs)

Browse all the conditions that are associated with Thrombocytopenia:

Thrombocytopenia (4,870 conditions)

Related publications that referenced our studies

YavasogluI, I., TurgutkayaII, A., & BolamanIII, Z., "Chlorella-induced thrombocytopenia", DATA, 2018 Jan .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .
YavasogluI, I., TurgutkayaII, A., & BolamanIII, Z., "Chlorella-induced thrombocytopenia", DATA, 2018 Jan .
Rasmy A, Rahal M, Kisana M, Ahmad S, Salah A, "Morphine induced thrombocytopenia: A case report", Journal of Case Reports and Images in Oncology, 2015 Dec .
Onder H, Arsava EM, Arat A, Topcuoglu MA, "Acute middle cerebral artery occlusion treated by thrombectomy in a patient with myelodysplastic syndrome and severe thrombocytopenia", Journal of vascular and interventional neurology, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on afatinib dimaleate (the active ingredients of Gilotrif) and Gilotrif (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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