Gleevec and Arthropathy - a phase IV clinical study of FDA data

Summary:

Arthropathy is reported as a side effect among people who take Gleevec (imatinib mesylate), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Aldactone, and have Hyperaldosteronism.

The phase IV clinical study analyzes which people have Arthropathy when taking Gleevec. It is created by eHealthMe based on reports of 35,000 people who have side effects when taking Gleevec from the FDA, and is updated regularly.

What is Gleevec?

Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.

What is Arthropathy?

Arthropathy is found to be associated with 1,609 drugs and 1,682 conditions by eHealthMe. Check the latest studies of Arthropathy.

On Jul, 16, 2026

35,000 people reported to have side effects when taking Gleevec.
Among them, 44 people (0.13%) have Arthropathy.

Among these 44 people:

How long have people been on Gleevec when they have Arthropathy? *

What is the gender of people who have Arthropathy when taking Gleevec? *

female: 58.14 %
male: 41.86 %

What is the age of people who have Arthropathy when taking Gleevec? *

What are other drugs people take besides Gleevec? *

What are other side effects people have besides Arthropathy? *

Oedema Peripheral (superficial swelling): 9 people, 20.45%
Muscle Spasms (muscle contraction): 9 people, 20.45%
Fatigue (feeling of tiredness): 9 people, 20.45%
Pain In Extremity: 7 people, 15.91%
Rashes (redness): 6 people, 13.64%
Joint Pain: 6 people, 13.64%
Feeling Abnormal: 6 people, 13.64%
Nausea (feeling of having an urge to vomit): 6 people, 13.64%
Diarrhea: 6 people, 13.64%
Pain: 5 people, 11.36%

What are the existing conditions these people have? *

Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 4 people, 9.09%
Hyperaldosteronism: 4 people, 9.09%
Gastrointestinal Stromal Tumor: 3 people, 6.82%
Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 4.55%
Breast Cancer: 2 people, 4.55%
Muscle Spasms (muscle contraction): 2 people, 4.55%
Depression: 2 people, 4.55%
Leukaemia (blood or bone marrow cancer): 2 people, 4.55%
Amoebic Dysentery (dysentery caused primarily by the amoeba entamoeba histolytica): 1 person, 2.27%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 2.27%

* Approximation only. Some reports may have incomplete information.

Do you take Gleevec and have Arthropathy?

- Check whether Arthropathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gleevec:

Gleevec (35,415 reports)

Arthropathy treatments and more:

Arthropathy (75,984 reports)

Browse all side effects of Gleevec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Arthropathy:

Arthropathy (1,609 drugs)

Browse all the conditions that are associated with Arthropathy:

Arthropathy (1,682 conditions)

Related publications that referenced our studies

O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on imatinib mesylate (the active ingredients of Gleevec) and Gleevec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.