Gleevec and Hiccups - a phase IV clinical study of FDA data
Summary:
Hiccups is reported as a side effect among people who take Gleevec (imatinib mesylate), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Oxycontin, and have Gastrointestinal stromal tumor.
The phase IV clinical study analyzes which people have Hiccups when taking Gleevec. It is created by eHealthMe based on reports of 35,000 people who have side effects when taking Gleevec from the FDA, and is updated regularly.
What is Gleevec?
Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.
What is Hiccups?
Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough) is found to be associated with 697 drugs and 1,180 conditions by eHealthMe. Check the latest studies of Hiccups.
35,000 people reported to have side effects when taking Gleevec.
Among them, 27 people (0.08%) have Hiccups.

Among these 27 people:
How long have people been on Gleevec when they have Hiccups? *
- < 1 month: 0.0 %
- 1 - 6 months: 14.29 %
- 6 - 12 months: 57.14 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 28.57 %
- 10+ years: 0.0 %
What is the gender of people who have Hiccups when taking Gleevec? *
- female: 3.7 %
- male: 96.3 %
What is the age of people who have Hiccups when taking Gleevec? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 0.0 %
- 40-49: 0.0 %
- 50-59: 38.1 %
- 60+: 61.9 %
What are other drugs people take besides Gleevec? *
- Percocet: 5 people, 18.52%
- Oxycontin: 5 people, 18.52%
- Ditropan: 4 people, 14.81%
- Allopurinol: 4 people, 14.81%
- Adalat: 3 people, 11.11%
- Bisoprolol Fumarate: 2 people, 7.41%
- Avalide: 1 person, 3.70%
What are other side effects people have besides Hiccups? *
- Nausea (feeling of having an urge to vomit): 15 people, 55.56%
- Hypotension (abnormally low blood pressure): 9 people, 33.33%
- Fever: 8 people, 29.63%
- Dry Mouth: 8 people, 29.63%
- Pain: 8 people, 29.63%
- Stomatitis (inflammation of mucous membrane of mouth): 8 people, 29.63%
- Rashes (redness): 7 people, 25.93%
- Urticaria (rash of round, red welts on the skin that itch intensely): 7 people, 25.93%
- White Blood Cell Count Increased: 5 people, 18.52%
- Poor Quality Sleep: 5 people, 18.52%
What are the existing conditions these people have? *
- Gastrointestinal Stromal Tumor: 11 people, 40.74%
- Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 5 people, 18.52%
- Stomatitis (inflammation of mucous membrane of mouth): 3 people, 11.11%
- Cardiomyopathy (weakening of the heart muscle): 2 people, 7.41%
- Small Intestine Carcinoma (cancer tumour of small intestine): 1 person, 3.70%
- Myeloid Leukaemia (a type of cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 3.70%
* Approximation only. Some reports may have incomplete information.
Do you take Gleevec and have Hiccups?
- Check whether Hiccups is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Gleevec:
- Gleevec (35,415 reports)
Hiccups treatments and more:
- Hiccups (10,643 reports)
How severe was Hiccups and when was it recovered:
Expand to all the drugs that have ingredients of imatinib mesylate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gleevec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Hiccups:
- Hiccups (697 drugs)
Browse all the conditions that are associated with Hiccups:
- Hiccups (1,180 conditions)
Related publications that referenced our studies
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
How the study uses the data?
The study uses data from the FDA. It is based on imatinib mesylate (the active ingredients of Gleevec) and Gleevec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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