Gleevec and Mental impairment - a phase IV clinical study of FDA data
Summary:
Mental impairment is reported as a side effect among people who take Gleevec (imatinib mesylate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ativan, and have Depression.
The phase IV clinical study analyzes which people have Mental impairment when taking Gleevec. It is created by eHealthMe based on reports of 35,000 people who have side effects when taking Gleevec from the FDA, and is updated regularly.
What is Gleevec?
Gleevec has active ingredients of imatinib mesylate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 35,415 Gleevec users. Check the latest studies of Gleevec.
What is Mental impairment?
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition) is found to be associated with 1,337 drugs and 1,315 conditions by eHealthMe. Check the latest studies of Mental impairment.
35,000 people reported to have side effects when taking Gleevec.
Among them, 30 people (0.09%) have Mental impairment.

Among these 30 people:
How long have people been on Gleevec when they have Mental impairment? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Mental impairment when taking Gleevec? *
- female: 66.67 %
- male: 33.33 %
What is the age of people who have Mental impairment when taking Gleevec? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 11.11 %
- 20-29: 5.56 %
- 30-39: 5.56 %
- 40-49: 5.56 %
- 50-59: 16.67 %
- 60+: 55.56 %
What are other drugs people take besides Gleevec? *
- Tylenol: 3 people, 10.00%
- Ativan: 3 people, 10.00%
- Methotrexate: 2 people, 6.67%
- Wellbutrin: 2 people, 6.67%
- Sprycel: 2 people, 6.67%
- Vitamin B12: 2 people, 6.67%
- Cytarabine: 2 people, 6.67%
- Lasix: 2 people, 6.67%
- Zoloft: 2 people, 6.67%
- Klonopin: 1 person, 3.33%
What are other side effects people have besides Mental impairment? *
- Fatigue (feeling of tiredness): 12 people, 40.00%
- Diarrhea: 8 people, 26.67%
- Nausea And Vomiting: 7 people, 23.33%
- Nausea (feeling of having an urge to vomit): 6 people, 20.00%
- Malaise (a feeling of general discomfort or uneasiness): 5 people, 16.67%
- Memory Loss: 5 people, 16.67%
- Thrombocytopenia (decrease of platelets in blood): 5 people, 16.67%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 5 people, 16.67%
- High Blood Pressure: 4 people, 13.33%
- Weakness: 4 people, 13.33%
What are the existing conditions these people have? *
- Depression: 2 people, 6.67%
- Vitamin B12 Deficiency: 1 person, 3.33%
- Diabetes: 1 person, 3.33%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 1 person, 3.33%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 3.33%
- Chest Pain: 1 person, 3.33%
- Chordoma (a brain tumour from the embryo): 1 person, 3.33%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 3.33%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 3.33%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 3.33%
* Approximation only. Some reports may have incomplete information.
Do you take Gleevec and have Mental impairment?
- Check whether Mental impairment is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Gleevec:
- Gleevec (35,415 reports)
Mental impairment treatments and more:
- Mental impairment (27,670 reports)
How severe was Mental impairment and when was it recovered:
Expand to all the drugs that have ingredients of imatinib mesylate:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Gleevec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Mental impairment:
- Mental impairment (1,337 drugs)
Browse all the conditions that are associated with Mental impairment:
- Mental impairment (1,315 conditions)
Related publications that referenced our studies
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
- Momtaz YA, Hamid TA, Ibrahim R, "The impact of mild cognitive impairment on sexual activity", American Journal of Alzheimer's Disease & Other Dementias?, 2013 Jan .
- O'rafferty C, McElligott F, Storey L, O'marcaigh A, Smith O, "Pneumatosis intestinalis and imatinib mesylate", Annals of hematology, 2014 Oct .
- Momtaz YA, Hamid TA, Ibrahim R, "The impact of mild cognitive impairment on sexual activity", American Journal of Alzheimer's Disease & Other Dementias?, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on imatinib mesylate (the active ingredients of Gleevec) and Gleevec (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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