Glipizide and Salivary hypersecretion - a phase IV clinical study of FDA data

Summary:

Salivary hypersecretion is reported as a side effect among people who take Glipizide (glipizide), especially for people who are male, 60+ old, also take Lisinopril, and have Schizoaffective disorder bipolar type.

The phase IV clinical study analyzes which people have Salivary hypersecretion when taking Glipizide. It is created by eHealthMe based on reports of 63,661 people who have side effects when taking Glipizide from the FDA, and is updated regularly.

What is Glipizide?

Glipizide has active ingredients of glipizide. It is often used in diabetes. eHealthMe is studying from 64,852 Glipizide users. Check the latest studies of Glipizide.

What is Salivary hypersecretion?

Salivary hypersecretion (excess saliva secretion) is found to be associated with 779 drugs and 1,338 conditions by eHealthMe. Check the latest studies of Salivary hypersecretion.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

63,661 people reported to have side effects when taking Glipizide.
Among them, 24 people (0.04%) have Salivary hypersecretion.

Could Glipizide cause Salivary hypersecretion?

Among these 24 people:

What is the gender of people who have Salivary hypersecretion when taking Glipizide? *

female: 34.78 %
male: 65.22 %

What is the age of people who have Salivary hypersecretion when taking Glipizide? *

What are other drugs people take besides Glipizide? *

What are other side effects people have besides Salivary hypersecretion? *

Agitation (state of anxiety or nervous excitement): 6 people, 25.00%
Mania (a state of abnormally elevated or irritable mood): 5 people, 20.83%
Fall: 4 people, 16.67%
Nausea (feeling of having an urge to vomit): 4 people, 16.67%
Drug Ineffective: 4 people, 16.67%
Psychotic Disorder: 4 people, 16.67%
Suicidal Ideation: 4 people, 16.67%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 4 people, 16.67%
Weakness: 3 people, 12.50%
Nausea And Vomiting: 3 people, 12.50%

What are the existing conditions these people have? *

Urinary Tract Infection: 5 people, 20.83%
Schizoaffective Disorder Bipolar Type (mental illness featuring schizophrenia and a mood disorder with mania): 5 people, 20.83%
Psychotic Disorder: 3 people, 12.50%
Hallucinations (sensations that appear real but are created by your mind): 3 people, 12.50%
Delusion (a false belief or opinion): 3 people, 12.50%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 12.50%
Multiple Myeloma (cancer of the plasma cells): 2 people, 8.33%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 4.17%
Parkinson's Disease: 1 person, 4.17%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 1 person, 4.17%

* Approximation only. Some reports may have incomplete information.

Do you take Glipizide and have Salivary hypersecretion?

- Check whether Salivary hypersecretion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glipizide:

Glipizide (64,852 reports)

Browse all side effects of Glipizide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Salivary hypersecretion:

Salivary hypersecretion (779 drugs)

Browse all the conditions that are associated with Salivary hypersecretion:

Salivary hypersecretion (1,338 conditions)

Related publications that referenced our studies

Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .
Das S, Anand Ramasamy SD, Mondal S, "An unusual case of glipizide-induced proximal myopathy", Journal of pharmacology & pharmacotherapeutics, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on glipizide (the active ingredients of Glipizide) and Glipizide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.