Glucophage xr and Fever - a phase IV clinical study of FDA data

Summary:

Fever is reported as a side effect among people who take Glucophage xr (metformin hydrochloride), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Lipitor, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Fever when taking Glucophage xr. It is created by eHealthMe based on reports of 3,773 people who have side effects when taking Glucophage xr from the FDA, and is updated regularly.

What is Glucophage xr?

Glucophage xr has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 3,939 Glucophage xr users. Check the latest studies of Glucophage xr.

What is Fever?

Fever is found to be associated with 3,494 drugs and 6,195 conditions by eHealthMe. Check the latest studies of Fever.



On Apr, 29, 2026

3,773 people reported to have side effects when taking Glucophage xr.
Among them, 36 people (0.95%) have Fever.

Could Glucophage xr cause Fever?

Among these 36 people:

How long have people been on Glucophage xr when they have Fever? *

  • < 1 month: 50 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fever when taking Glucophage xr? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Fever when taking Glucophage xr? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.94 %
  • 20-29: 2.94 %
  • 30-39: 2.94 %
  • 40-49: 20.59 %
  • 50-59: 47.06 %
  • 60+: 23.53 %

What are other drugs people take besides Glucophage xr? *

  1. Lipitor: 9 people, 25.00%
  2. Norvasc: 8 people, 22.22%
  3. Tylenol: 8 people, 22.22%
  4. Potassium Chloride: 7 people, 19.44%
  5. Zetia: 6 people, 16.67%
  6. Protonix: 6 people, 16.67%
  7. Zofran: 6 people, 16.67%
  8. Furosemide: 6 people, 16.67%
  9. Aspirin: 5 people, 13.89%
  10. Brilinta: 5 people, 13.89%

What are other side effects people have besides Fever? *

  1. Rashes (redness): 9 people, 25.00%
  2. Chest Pain: 9 people, 25.00%
  3. Weakness: 8 people, 22.22%
  4. Chills (felling of cold): 7 people, 19.44%
  5. Pain: 7 people, 19.44%
  6. Gait Disturbance: 7 people, 19.44%
  7. Joint Pain: 6 people, 16.67%
  8. Back Pain: 6 people, 16.67%
  9. Fatigue (feeling of tiredness): 6 people, 16.67%
  10. Nausea (feeling of having an urge to vomit): 6 people, 16.67%

What are the existing conditions these people have? *

  1. Immune System Disorder: 4 people, 11.11%
  2. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 11.11%
  3. Stress And Anxiety: 3 people, 8.33%
  4. Primary Progressive Multiple Sclerosis (primary progressive inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 8.33%
  5. Muscle Spasms (muscle contraction): 3 people, 8.33%
  6. Weakness: 2 people, 5.56%
  7. Osteoporosis (bones weak and more likely to break): 2 people, 5.56%
  8. Balance Disorder: 2 people, 5.56%
  9. Central Nervous System Lesion (an abnormality in tissue of brain or spinal cord): 2 people, 5.56%
  10. Chronic Thyroiditis (long lasting inflammation of thyroid gland): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Glucophage xr and have Fever?

- Check whether Fever is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glucophage xr:

Fever treatments and more:

  • Fever (498,666 reports)

How severe was Fever and when was it recovered:

Expand to all the drugs that have ingredients of metformin hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glucophage xr:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fever:

Browse all the conditions that are associated with Fever:

  • Fever (6,195 conditions)

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on metformin hydrochloride (the active ingredients of Glucophage xr) and Glucophage xr (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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