Glucovance and Adverse event - a phase IV clinical study of FDA data

Summary:

Adverse event is reported as a side effect among people who take Glucovance (glyburide; metformin hydrochloride), especially for people who are female, 60+ old, also take Toprol-Xl, and have High blood cholesterol.

The phase IV clinical study analyzes which people have Adverse event when taking Glucovance. It is created by eHealthMe based on reports of 6,238 people who have side effects when taking Glucovance from the FDA, and is updated regularly.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.

What is Adverse event?

Adverse event is found to be associated with 1,688 drugs and 1,665 conditions by eHealthMe. Check the latest studies of Adverse event.

On Jul, 13, 2026

6,238 people reported to have side effects when taking Glucovance.
Among them, 12 people (0.19%) have Adverse event.

Among these 12 people:

What is the gender of people who have Adverse event when taking Glucovance? *

female: 75 %
male: 25 %

What is the age of people who have Adverse event when taking Glucovance? *

What are other drugs people take besides Glucovance? *

What are other side effects people have besides Adverse event? *

Nausea (feeling of having an urge to vomit): 5 people, 41.67%
Fatigue (feeling of tiredness): 4 people, 33.33%
Dizziness: 4 people, 33.33%
Fall: 3 people, 25.00%
Confusional State: 3 people, 25.00%
Weakness: 3 people, 25.00%
Urinary Tract Infection: 3 people, 25.00%
Speech Impairment (Adult) (inability to speak (adult)): 3 people, 25.00%
High Blood Pressure: 3 people, 25.00%
Confusion: 3 people, 25.00%

What are the existing conditions these people have? *

High Blood Cholesterol: 2 people, 16.67%
Thyroiditis (inflammation of thyroid gland): 1 person, 8.33%
Sleep Disorder: 1 person, 8.33%
Neck Pain: 1 person, 8.33%
Muscle Spasms (muscle contraction): 1 person, 8.33%
Low Density Lipoprotein Increased (cholesterol increased in blood): 1 person, 8.33%
Blood Pressure Abnormal: 1 person, 8.33%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Glucovance and have Adverse event?

- Check whether Adverse event is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glucovance:

Glucovance (6,302 reports)

Adverse event treatments and more:

Adverse event (100,133 reports)

How severe was Adverse event and when was it recovered:

Adverse event in Glucovance

Expand to all the drugs that have ingredients of glyburide; metformin hydrochloride:

Adverse event and drugs with ingredients of glyburide; metformin hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glucovance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Adverse event:

Adverse event (1,688 drugs)

Browse all the conditions that are associated with Adverse event:

Adverse event (1,665 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glyburide; metformin hydrochloride (the active ingredients of Glucovance) and Glucovance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.