Glucovance and Chronic obstructive pulmonary disease - a phase IV clinical study of FDA data

Summary:

Chronic obstructive pulmonary disease is reported as a side effect among people who take Glucovance (glyburide; metformin hydrochloride), especially for people who are female, 60+ old, also take Lasix, and have Bone disorder.

The phase IV clinical study analyzes which people have Chronic obstructive pulmonary disease when taking Glucovance. It is created by eHealthMe based on reports of 6,238 people who have side effects when taking Glucovance from the FDA, and is updated regularly.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.

What is Chronic obstructive pulmonary disease?

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe) is found to be associated with 1,809 drugs and 2,206 conditions by eHealthMe. Check the latest studies of Chronic obstructive pulmonary disease.

On Jul, 06, 2026

6,238 people reported to have side effects when taking Glucovance.
Among them, 70 people (1.12%) have Chronic obstructive pulmonary disease.

Could Glucovance cause Chronic obstructive pulmonary disease?

Among these 70 people:

What is the gender of people who have Chronic obstructive pulmonary disease when taking Glucovance? *

female: 51.43 %
male: 48.57 %

What is the age of people who have Chronic obstructive pulmonary disease when taking Glucovance? *

What are other drugs people take besides Glucovance? *

What are other side effects people have besides Chronic obstructive pulmonary disease? *

Pneumonia: 42 people, 60.00%
Dyspnea (difficult or laboured breathing): 40 people, 57.14%
Cardiac Failure Congestive: 39 people, 55.71%
Stress And Anxiety: 38 people, 54.29%
Oedema Peripheral (superficial swelling): 37 people, 52.86%
Pain: 37 people, 52.86%
Back Pain: 35 people, 50.00%
Joint Pain: 35 people, 50.00%
Cellulitis (infection under the skin): 33 people, 47.14%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 32 people, 45.71%

What are the existing conditions these people have? *

Bone Disorder: 17 people, 24.29%
Multiple Myeloma (cancer of the plasma cells): 10 people, 14.29%
Metastases To Bone (cancer spreads to bone): 7 people, 10.00%
High Blood Pressure: 6 people, 8.57%
Osteolysis (dissolution of bone): 5 people, 7.14%
Depression: 5 people, 7.14%
Stress And Anxiety: 5 people, 7.14%
Resorption Bone Increased: 4 people, 5.71%
Postpartum Depression (depression suffered by a mother following childbirth): 4 people, 5.71%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 5.71%

* Approximation only. Some reports may have incomplete information.

Do you take Glucovance and have Chronic obstructive pulmonary disease?

- Check whether Chronic obstructive pulmonary disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glucovance:

Glucovance (6,302 reports)

Chronic obstructive pulmonary disease treatments and more:

Chronic obstructive pulmonary disease (198,253 reports)

How severe was Chronic obstructive pulmonary disease and when was it recovered:

Chronic obstructive pulmonary disease in Glucovance

Expand to all the drugs that have ingredients of glyburide; metformin hydrochloride:

Chronic obstructive pulmonary disease and drugs with ingredients of glyburide; metformin hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glucovance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chronic obstructive pulmonary disease:

Chronic obstructive pulmonary disease (1,809 drugs)

Browse all the conditions that are associated with Chronic obstructive pulmonary disease:

Chronic obstructive pulmonary disease (2,206 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glyburide; metformin hydrochloride (the active ingredients of Glucovance) and Glucovance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.