Glucovance and Hepatitis aggravated - a phase IV clinical study of FDA data

Summary:

Hepatitis aggravated is reported as a side effect among people who take Glucovance (glyburide; metformin hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Glucophage, and have Metastases to prostate.

The phase IV clinical study analyzes which people have Hepatitis aggravated when taking Glucovance. It is created by eHealthMe based on reports of 6,238 people who have side effects when taking Glucovance from the FDA, and is updated regularly.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.

What is Hepatitis aggravated?

Hepatitis aggravated is found to be associated with 1,156 drugs and 433 conditions by eHealthMe. Check the latest studies of Hepatitis aggravated.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

6,238 people reported to have side effects when taking Glucovance.
Among them, 26 people (0.42%) have Hepatitis aggravated.

Could Glucovance cause Hepatitis aggravated?

Among these 26 people:

How long have people been on Glucovance when they have Hepatitis aggravated? *

What is the gender of people who have Hepatitis aggravated when taking Glucovance? *

female: 36 %
male: 64 %

What is the age of people who have Hepatitis aggravated when taking Glucovance? *

What are other drugs people take besides Glucovance? *

What are other side effects people have besides Hepatitis aggravated? *

Stress And Anxiety: 12 people, 46.15%
Weight Decreased: 12 people, 46.15%
Headache (pain in head): 11 people, 42.31%
Pain: 11 people, 42.31%
Fainting (loss of consciousness and postural tone): 11 people, 42.31%
Hypoaesthesia (reduced sense of touch or sensation): 11 people, 42.31%
Anaemia (lack of blood): 11 people, 42.31%
Weakness: 11 people, 42.31%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 11 people, 42.31%
Loss Of Consciousness: 10 people, 38.46%

What are the existing conditions these people have? *

Metastases To Prostate (cancer spreads to prostate): 2 people, 7.69%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 3.85%
Osteoporosis (bones weak and more likely to break): 1 person, 3.85%
Neuropathy Peripheral (surface nerve damage): 1 person, 3.85%
Joint Pain: 1 person, 3.85%
Depression: 1 person, 3.85%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 1 person, 3.85%

* Approximation only. Some reports may have incomplete information.

Do you take Glucovance and have Hepatitis aggravated?

- Check whether Hepatitis aggravated is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glucovance:

Glucovance (6,302 reports)

Hepatitis aggravated treatments and more:

Hepatitis aggravated (33 reports)

How severe was Hepatitis aggravated and when was it recovered:

Hepatitis aggravated in Glucovance

Expand to all the drugs that have ingredients of glyburide; metformin hydrochloride:

Hepatitis aggravated and drugs with ingredients of glyburide; metformin hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glucovance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hepatitis aggravated:

Hepatitis aggravated (1,157 drugs)

Browse all the conditions that are associated with Hepatitis aggravated:

Hepatitis aggravated (433 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glyburide; metformin hydrochloride (the active ingredients of Glucovance) and Glucovance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.