Glucovance and Ventricular arrhythmia - a phase IV clinical study of FDA data

Summary:

Ventricular arrhythmia is reported as a side effect among people who take Glucovance (glyburide; metformin hydrochloride), especially for people who are male, 50-59 old, also take Revatio, and have Pulmonary hypertension.

The phase IV clinical study analyzes which people have Ventricular arrhythmia when taking Glucovance. It is created by eHealthMe based on reports of 6,238 people who have side effects when taking Glucovance from the FDA, and is updated regularly.

What is Glucovance?

Glucovance has active ingredients of glyburide; metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 6,302 Glucovance users. Check the latest studies of Glucovance.

What is Ventricular arrhythmia?

Ventricular arrhythmia (problem with the rate or rhythm of the heartbeat) is found to be associated with 478 drugs and 559 conditions by eHealthMe. Check the latest studies of Ventricular arrhythmia.

On Jul, 14, 2026

6,238 people reported to have side effects when taking Glucovance.
Among them, 13 people (0.21%) have Ventricular arrhythmia.

Could Glucovance cause Ventricular arrhythmia?

Among these 13 people:

What is the gender of people who have Ventricular arrhythmia when taking Glucovance? *

female: 25 %
male: 75 %

What is the age of people who have Ventricular arrhythmia when taking Glucovance? *

What are other drugs people take besides Glucovance? *

What are other side effects people have besides Ventricular arrhythmia? *

Hyperlactacidaemia (the acidosis and also reduces the capacity of the kidney): 9 people, 69.23%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 9 people, 69.23%
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin): 9 people, 69.23%
Dyspnea (difficult or laboured breathing): 7 people, 53.85%
Hepatic Failure (liver failure): 7 people, 53.85%
Insomnia (sleeplessness): 7 people, 53.85%
Heart Palpitations (feelings or sensations that your heart is pounding or racing): 3 people, 23.08%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 23.08%
Thyroid Diseases: 2 people, 15.38%
Indigestion: 2 people, 15.38%

What are the existing conditions these people have? *

Pulmonary Hypertension (increase in blood pressure in the lung artery): 9 people, 69.23%
Hiv Infection: 8 people, 61.54%
Depression: 6 people, 46.15%
Hiv Test Positive: 1 person, 7.69%
Cardiac Failure Congestive: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Glucovance and have Ventricular arrhythmia?

- Check whether Ventricular arrhythmia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glucovance:

Glucovance (6,302 reports)

Ventricular arrhythmia treatments and more:

Ventricular arrhythmia (5,065 reports)

How severe was Ventricular arrhythmia and when was it recovered:

Ventricular arrhythmia in Glucovance

Expand to all the drugs that have ingredients of glyburide; metformin hydrochloride:

Ventricular arrhythmia and drugs with ingredients of glyburide; metformin hydrochloride

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glucovance:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ventricular arrhythmia:

Ventricular arrhythmia (478 drugs)

Browse all the conditions that are associated with Ventricular arrhythmia:

Ventricular arrhythmia (559 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on glyburide; metformin hydrochloride (the active ingredients of Glucovance) and Glucovance (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.