Glutathione and Depression - a phase IV clinical study of FDA data

Summary:

Depression is reported as a side effect among people who take Glutathione (glutathione), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Ursodiol, and have Bone marrow conditioning regimen.

The phase IV clinical study analyzes which people have Depression when taking Glutathione. It is created by eHealthMe based on reports of 1,987 people who have side effects when taking Glutathione from the FDA, and is updated regularly.

What is Glutathione?

Glutathione has active ingredients of glutathione. eHealthMe is studying from 2,147 Glutathione users. Check the latest studies of Glutathione.

What is Depression?

Depression is found to be associated with 3,168 drugs and 4,130 conditions by eHealthMe. Check the latest studies of Depression.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

1,987 people reported to have side effects when taking Glutathione.
Among them, 46 people (2.32%) have Depression.

Could Glutathione cause Depression?

Among these 46 people:

How long have people been on Glutathione when they have Depression? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 100 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Depression when taking Glutathione? *

  • female: 75 %
  • male: 25 %

What is the age of people who have Depression when taking Glutathione? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.11 %
  • 20-29: 27.78 %
  • 30-39: 5.56 %
  • 40-49: 8.33 %
  • 50-59: 19.44 %
  • 60+: 27.78 %

What are other drugs people take besides Glutathione? *

  1. Ursodiol: 13 people, 28.26%
  2. Tacrolimus: 12 people, 26.09%
  3. Hydrocortisone Sodium Succinate: 12 people, 26.09%
  4. Methotrexate: 12 people, 26.09%
  5. Famotidine: 12 people, 26.09%
  6. Prednisolone: 12 people, 26.09%
  7. Sulfamethoprim: 12 people, 26.09%
  8. Micafungin Sodium: 12 people, 26.09%
  9. Methylprednisolone Sodium Succinate: 11 people, 23.91%
  10. Hydroxyzine Hydrochloride: 11 people, 23.91%

What are other side effects people have besides Depression? *

  1. Insomnia (sleeplessness): 31 people, 67.39%
  2. Nausea (feeling of having an urge to vomit): 24 people, 52.17%
  3. Pain: 23 people, 50.00%
  4. Stress And Anxiety: 23 people, 50.00%
  5. Fatigue (feeling of tiredness): 20 people, 43.48%
  6. Diarrhea: 17 people, 36.96%
  7. Feeling Abnormal: 16 people, 34.78%
  8. Joint Pain: 15 people, 32.61%
  9. Memory Loss: 13 people, 28.26%
  10. Renal Impairment (severely reduced kidney function): 13 people, 28.26%

What are the existing conditions these people have? *

  1. Bone Marrow Conditioning Regimen: 12 people, 26.09%
  2. White Blood Cell Count Abnormal: 6 people, 13.04%
  3. Cystic Fibrosis (disease of the secretary glands): 6 people, 13.04%
  4. Ewing's Sarcoma Recurrent (malignant small, round, blue cell tumour- recurrent): 6 people, 13.04%
  5. Urinary Tract Infection: 6 people, 13.04%
  6. Ovarian Cancer (cancer of ovary): 5 people, 10.87%
  7. Pain: 5 people, 10.87%
  8. Ovarian Epithelial Cancer (cancer that begins in the cells on the surface of the ovary): 5 people, 10.87%
  9. Ovarian Cancer Stage Iii: 5 people, 10.87%
  10. Pseudomonas Infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa): 4 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Glutathione and have Depression?

- Check whether Depression is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glutathione:

Depression treatments and more:

How severe was Depression and when was it recovered:

Expand to all the drugs that have ingredients of glutathione:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Glutathione:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Depression:

Browse all the conditions that are associated with Depression:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glutathione (the active ingredients of Glutathione) and Glutathione (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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