Glycopyrrolate and Musculoskeletal stiffness - a phase IV clinical study of FDA data

Summary:

Musculoskeletal stiffness is reported as a side effect among people who take Glycopyrrolate (glycopyrrolate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Singulair, and have Asthma.

The phase IV clinical study analyzes which people have Musculoskeletal stiffness when taking Glycopyrrolate. It is created by eHealthMe based on reports of 5,510 people who have side effects when taking Glycopyrrolate from the FDA, and is updated regularly.

What is Glycopyrrolate?

Glycopyrrolate has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 5,599 Glycopyrrolate users. Check the latest studies of Glycopyrrolate.

What is Musculoskeletal stiffness?

Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves) is found to be associated with 1,960 drugs and 1,916 conditions by eHealthMe. Check the latest studies of Musculoskeletal stiffness.

On Jul, 16, 2026

5,510 people reported to have side effects when taking Glycopyrrolate.
Among them, 62 people (1.13%) have Musculoskeletal stiffness.

Could Glycopyrrolate cause Musculoskeletal stiffness?

Among these 62 people:

How long have people been on Glycopyrrolate when they have Musculoskeletal stiffness? *

What is the gender of people who have Musculoskeletal stiffness when taking Glycopyrrolate? *

female: 81.63 %
male: 18.37 %

What is the age of people who have Musculoskeletal stiffness when taking Glycopyrrolate? *

What are other drugs people take besides Glycopyrrolate? *

Singulair: 27 people, 43.55%
Abilify: 24 people, 38.71%
Aripiprazole: 24 people, 38.71%
Xolair: 18 people, 29.03%
Montelukast Sodium: 18 people, 29.03%
Mupirocin: 16 people, 25.81%
Albuterol: 12 people, 19.35%
Ventolin: 7 people, 11.29%
Venlafaxine Hydrochloride: 7 people, 11.29%
Prednisone: 7 people, 11.29%

What are other side effects people have besides Musculoskeletal stiffness? *

Cough: 37 people, 59.68%
Fatigue (feeling of tiredness): 36 people, 58.06%
Joint Pain: 33 people, 53.23%
Dyspnea (difficult or laboured breathing): 32 people, 51.61%
Weight Decreased: 31 people, 50.00%
High Blood Pressure: 30 people, 48.39%
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 30 people, 48.39%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 30 people, 48.39%
Sneezing: 29 people, 46.77%
Headache (pain in head): 29 people, 46.77%

What are the existing conditions these people have? *

Asthma: 31 people, 50.00%
The Flu (the flu is caused by an influenza virus): 20 people, 32.26%
Parkinson's Disease: 7 people, 11.29%
Diabetes: 6 people, 9.68%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 6.45%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 6.45%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 6.45%
Delusion (a false belief or opinion): 4 people, 6.45%
Hallucinations (sensations that appear real but are created by your mind): 4 people, 6.45%
Hypersensitivity: 4 people, 6.45%

* Approximation only. Some reports may have incomplete information.

Do you take Glycopyrrolate and have Musculoskeletal stiffness?

- Check whether Musculoskeletal stiffness is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Glycopyrrolate:

Glycopyrrolate (5,599 reports)

Browse all side effects of Glycopyrrolate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Musculoskeletal stiffness:

Musculoskeletal stiffness (1,960 drugs)

Browse all the conditions that are associated with Musculoskeletal stiffness:

Musculoskeletal stiffness (1,916 conditions)

Related publications that referenced our studies

D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .
D'souza S, Gowler V, "Glycopyrrolate‐induced respiratory arrest: an unusual side effect", Acta Anaesthesiologica Scandinavica, 2015 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on glycopyrrolate (the active ingredients of Glycopyrrolate) and Glycopyrrolate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.