Gravol and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Gravol (dimenhydrinate), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Benadryl, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Gravol. It is created by eHealthMe based on reports of 6,796 people who have side effects when taking Gravol from the FDA, and is updated regularly.

What is Gravol?

Gravol has active ingredients of dimenhydrinate. It is often used in nausea. eHealthMe is studying from 7,192 Gravol users. Check the latest studies of Gravol.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,047 drugs and 1,416 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.



On Nov, 20, 2025

6,796 people reported to have side effects when taking Gravol.
Among them, 19 people (0.28%) have Hyperthyroidism.

Could Gravol cause Hyperthyroidism?

Among these 19 people:

How long have people been on Gravol when they have Hyperthyroidism? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyperthyroidism when taking Gravol? *

  • female: 82.35 %
  • male: 17.65 %

What is the age of people who have Hyperthyroidism when taking Gravol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 6.67 %
  • 30-39: 46.67 %
  • 40-49: 40.0 %
  • 50-59: 6.67 %
  • 60+: 0.0 %

What are other drugs people take besides Gravol? *

  1. Benadryl: 12 people, 63.16%
  2. Paracetamol: 8 people, 42.11%
  3. Cimetidine: 5 people, 26.32%
  4. Zantac: 3 people, 15.79%
  5. Magnesium: 3 people, 15.79%
  6. Acyclovir: 3 people, 15.79%
  7. Botox: 3 people, 15.79%
  8. Effexor: 3 people, 15.79%
  9. Fish Oil: 3 people, 15.79%
  10. Acetaminophen: 3 people, 15.79%

What are other side effects people have besides Hyperthyroidism? *

  1. Lymphocyte Count Decreased: 15 people, 78.95%
  2. Headache (pain in head): 12 people, 63.16%
  3. Urine Abnormality: 11 people, 57.89%
  4. Blood Thyroid Stimulating Hormone Decreased: 9 people, 47.37%
  5. Hypotension (abnormally low blood pressure): 9 people, 47.37%
  6. Weight Increased: 8 people, 42.11%
  7. Rashes (redness): 8 people, 42.11%
  8. Back Pain: 8 people, 42.11%
  9. Fatigue (feeling of tiredness): 8 people, 42.11%
  10. Hyperhidrosis (abnormally increased sweating): 8 people, 42.11%

What are the existing conditions these people have? *

  1. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 13 people, 68.42%
  2. Muscle Spasms (muscle contraction): 5 people, 26.32%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 15.79%
  4. Constipation: 3 people, 15.79%
  5. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 10.53%
  6. High Blood Pressure: 1 person, 5.26%
  7. Bladder Dysfunction: 1 person, 5.26%
  8. Birth Control: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Gravol and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gravol:

Hyperthyroidism treatments and more:

How severe was Hyperthyroidism and when was it recovered:

Expand to all the drugs that have ingredients of dimenhydrinate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Gravol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Browse all the conditions that are associated with Hyperthyroidism:

Drugs similar to Gravol and Hyperthyroidism :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on dimenhydrinate (the active ingredients of Gravol) and Gravol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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