Gravol and Hypothyroidism - a phase IV clinical study of FDA data

Summary:

Hypothyroidism is reported as a side effect among people who take Gravol (dimenhydrinate), especially for people who are female, 30-39 old, have been taking the drug for < 1 month also take Benadryl, and have Relapsing-remitting multiple sclerosis.

The phase IV clinical study analyzes which people have Hypothyroidism when taking Gravol. It is created by eHealthMe based on reports of 6,796 people who have side effects when taking Gravol from the FDA, and is updated regularly.

What is Gravol?

Gravol has active ingredients of dimenhydrinate. It is often used in nausea. eHealthMe is studying from 7,192 Gravol users. Check the latest studies of Gravol.

What is Hypothyroidism?

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development) is found to be associated with 1,616 drugs and 2,600 conditions by eHealthMe. Check the latest studies of Hypothyroidism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

6,796 people reported to have side effects when taking Gravol.
Among them, 32 people (0.47%) have Hypothyroidism.

Among these 32 people:

How long have people been on Gravol when they have Hypothyroidism? *

What is the gender of people who have Hypothyroidism when taking Gravol? *

female: 100 %
male: 0.0 %

What is the age of people who have Hypothyroidism when taking Gravol? *

What are other drugs people take besides Gravol? *

What are other side effects people have besides Hypothyroidism? *

Lymphocyte Count Decreased: 27 people, 84.38%
Urine Abnormality: 25 people, 78.12%
Headache (pain in head): 23 people, 71.88%
Blood Urine Present: 21 people, 65.62%
White Blood Cells Urine Positive: 19 people, 59.38%
Blood Thyroid Stimulating Hormone Decreased: 18 people, 56.25%
Fatigue (feeling of tiredness): 17 people, 53.12%
Weakness: 15 people, 46.88%
Urine Leukocyte Esterase Positive: 15 people, 46.88%
White Blood Cell Count Decreased: 14 people, 43.75%

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 27 people, 84.38%
Muscle Spasms (muscle contraction): 7 people, 21.88%
Sleep Disorder: 6 people, 18.75%
Pain: 6 people, 18.75%
Bipolar Disorder (mood disorder): 6 people, 18.75%
Fatigue (feeling of tiredness): 6 people, 18.75%
Thyroid Diseases: 4 people, 12.50%
Back Pain: 2 people, 6.25%
Constipation: 2 people, 6.25%
Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Gravol and have Hypothyroidism?

- Check whether Hypothyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Gravol:

Gravol (7,192 reports)

Hypothyroidism treatments and more:

Hypothyroidism (168,067 reports)

Browse all side effects of Gravol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hypothyroidism:

Hypothyroidism (1,616 drugs)

Browse all the conditions that are associated with Hypothyroidism:

Hypothyroidism (2,600 conditions)

Related publications that referenced our studies

Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .
Ezeji GC, Inoue T, Bahtiyar G, Sacerdote A, "Hallucinations associated with miglitol use in a patient with chronic kidney disease and hypothyroidism", BMJ case reports, 2015 Feb .

How the study uses the data?

The study uses data from the FDA. It is based on dimenhydrinate (the active ingredients of Gravol) and Gravol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.