Guaifenesin and Herniated nucleus pulposus (slipped disk) - a phase IV clinical study of FDA data

Summary:

Herniated nucleus pulposus (slipped disk) is reported as a side effect among people who take Guaifenesin (guaifenesin), especially for people who are male, 50-59 old, have been taking the drug for < 1 month also take Singulair, and have Narcolepsy.

The phase IV clinical study analyzes which people have Herniated nucleus pulposus (slipped disk) when taking Guaifenesin. It is created by eHealthMe based on reports of 11,942 people who have side effects when taking Guaifenesin from the FDA, and is updated regularly.

What is Guaifenesin?

Guaifenesin has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 12,106 Guaifenesin users. Check the latest studies of Guaifenesin.

What is Herniated nucleus pulposus (slipped disk)?

Herniated nucleus pulposus (slipped disk) is found to be associated with 582 drugs and 909 conditions by eHealthMe. Check the latest studies of Herniated nucleus pulposus (slipped disk).

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

11,942 people reported to have side effects when taking Guaifenesin.
Among them, 14 people (0.12%) have Herniated nucleus pulposus (slipped disk).

Could Guaifenesin cause Herniated nucleus pulposus (slipped disk)?

Among these 14 people:

How long have people been on Guaifenesin when they have Herniated nucleus pulposus (slipped disk)? *

What is the gender of people who have Herniated nucleus pulposus (slipped disk) when taking Guaifenesin? *

female: 42.86 %
male: 57.14 %

What is the age of people who have Herniated nucleus pulposus (slipped disk) when taking Guaifenesin? *

What are other drugs people take besides Guaifenesin? *

What are other side effects people have besides Herniated nucleus pulposus (slipped disk)? *

Depression: 8 people, 57.14%
Intervertebral Disc Degeneration (spinal disc degeneration): 6 people, 42.86%
Neuropathy Peripheral (surface nerve damage): 6 people, 42.86%
Movement - Uncoordinated: 6 people, 42.86%
Memory Loss: 6 people, 42.86%
Stress And Anxiety: 6 people, 42.86%
Speech Impairment (Adult) (inability to speak (adult)): 6 people, 42.86%
High Blood Pressure: 5 people, 35.71%
Weakness: 5 people, 35.71%
Back Pain: 5 people, 35.71%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 42.86%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 35.71%
Nausea (feeling of having an urge to vomit): 4 people, 28.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 28.57%
Multiple Allergies (allergy to multiple agents): 3 people, 21.43%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 3 people, 21.43%
Dyspnea (difficult or laboured breathing): 3 people, 21.43%
Depression: 3 people, 21.43%
Pain: 3 people, 21.43%
Mood Swings (an extreme or rapid change in mood): 3 people, 21.43%

* Approximation only. Some reports may have incomplete information.

Do you take Guaifenesin and have Herniated nucleus pulposus (slipped disk)?

- Check whether Herniated nucleus pulposus (slipped disk) is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Guaifenesin:

Guaifenesin (12,106 reports)

Herniated nucleus pulposus (slipped disk) treatments and more:

Herniated nucleus pulposus (slipped disk) (5,608 reports)

How severe was Herniated nucleus pulposus (slipped disk) and when was it recovered:

Herniated nucleus pulposus (slipped disk) in Guaifenesin

Expand to all the drugs that have ingredients of guaifenesin:

Herniated nucleus pulposus (slipped disk) and drugs with ingredients of guaifenesin (27 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Guaifenesin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Herniated nucleus pulposus (slipped disk):

Herniated nucleus pulposus (slipped disk) (582 drugs)

Browse all the conditions that are associated with Herniated nucleus pulposus (slipped disk):

Herniated nucleus pulposus (slipped disk) (909 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin (the active ingredients of Guaifenesin) and Guaifenesin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.