Haldol and Tonic clonic movements - a phase IV clinical study of FDA data

Summary:

Tonic clonic movements is reported as a side effect among people who take Haldol (haloperidol), especially for people who are female, 40-49 old, have been taking the drug for 2 - 5 years also take Clozapine, and have Depression.

The phase IV clinical study analyzes which people have Tonic clonic movements when taking Haldol. It is created by eHealthMe based on reports of 22,656 people who have side effects when taking Haldol from the FDA, and is updated regularly.

What is Haldol?

Haldol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 23,102 Haldol users. Check the latest studies of Haldol.

What is Tonic clonic movements?

Tonic clonic movements (generalized seizure that affects the entire brain) is found to be associated with 127 drugs and 349 conditions by eHealthMe. Check the latest studies of Tonic clonic movements.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

22,656 people reported to have side effects when taking Haldol.
Among them, 16 people (0.07%) have Tonic clonic movements.

Could Haldol cause Tonic clonic movements?

Among these 16 people:

How long have people been on Haldol when they have Tonic clonic movements? *

What is the gender of people who have Tonic clonic movements when taking Haldol? *

female: 62.5 %
male: 37.5 %

What is the age of people who have Tonic clonic movements when taking Haldol? *

What are other drugs people take besides Haldol? *

What are other side effects people have besides Tonic clonic movements? *

Overdose: 9 people, 56.25%
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 9 people, 56.25%
Toxic Encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances): 8 people, 50.00%
Loss Of Consciousness: 4 people, 25.00%
Agitation (state of anxiety or nervous excitement): 4 people, 25.00%
Consciousness - Decreased: 3 people, 18.75%
Hallucinations (sensations that appear real but are created by your mind): 3 people, 18.75%
Confusional State: 3 people, 18.75%
Cardiac Arrest: 3 people, 18.75%
Drowsiness: 2 people, 12.50%

What are the existing conditions these people have? *

Depression: 8 people, 50.00%
Psychotic Disorder: 2 people, 12.50%
Psychomotor Hyperactivity (feelings of extreme restlessness): 2 people, 12.50%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 12.50%
Mania (a state of abnormally elevated or irritable mood): 2 people, 12.50%
High Blood Pressure: 2 people, 12.50%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 12.50%
Aggression: 2 people, 12.50%
Urinary Tract Infection: 1 person, 6.25%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Haldol and have Tonic clonic movements?

- Check whether Tonic clonic movements is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Haldol:

Haldol (23,102 reports)

Browse all side effects of Haldol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Tonic clonic movements:

Tonic clonic movements (127 drugs)

Browse all the conditions that are associated with Tonic clonic movements:

Tonic clonic movements (349 conditions)

Related publications that referenced our studies

Obayi, O., & Tagbo, N. , "Bilateral Pedal Oedema Associated with Intramuscular Haloperidol–A Rare Observation", International Neuropsychiatric Disease Journal, 2018 Jan .
Obayi, O., & Tagbo, N. , "Bilateral Pedal Oedema Associated with Intramuscular Haloperidol–A Rare Observation", International Neuropsychiatric Disease Journal, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on haloperidol (the active ingredients of Haldol) and Haldol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.