1. Home
  2. Analysis
  3. Haloperidol-decanoate
  4. Hyponatremia

Haloperidol decanoate and Hyponatremia - a phase IV clinical study of FDA data

Summary:

Hyponatremia is reported as a side effect among people who take Haloperidol decanoate (haloperidol decanoate), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Valproic Acid, and have Schizophrenia.

The phase IV clinical study analyzes which people have Hyponatremia when taking Haloperidol decanoate. It is created by eHealthMe based on reports of 1,886 people who have side effects when taking Haloperidol decanoate from the FDA, and is updated regularly.

What is Haloperidol decanoate?

Haloperidol decanoate has active ingredients of haloperidol decanoate. eHealthMe is studying from 1,890 Haloperidol decanoate users. Check the latest studies of Haloperidol decanoate.

What is Hyponatremia?

Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration) is found to be associated with 1,941 drugs and 2,277 conditions by eHealthMe. Check the latest studies of Hyponatremia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

1,886 people reported to have side effects when taking Haloperidol decanoate.
Among them, 14 people (0.74%) have Hyponatremia.

Could Haloperidol decanoate cause Hyponatremia?

Among these 14 people:

How long have people been on Haloperidol decanoate when they have Hyponatremia? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hyponatremia when taking Haloperidol decanoate? *

  • female: 46.15 %
  • male: 53.85 %

What is the age of people who have Hyponatremia when taking Haloperidol decanoate? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 9.09 %
  • 40-49: 27.27 %
  • 50-59: 27.27 %
  • 60+: 36.36 %

What are other drugs people take besides Haloperidol decanoate? *

  1. Valproic Acid: 3 people, 21.43%
  2. Haldol: 2 people, 14.29%
  3. Benztropine Mesylate: 2 people, 14.29%
  4. Levothyroxine Sodium: 2 people, 14.29%
  5. Olanzapine: 2 people, 14.29%
  6. Pantoprazole: 2 people, 14.29%
  7. Amlodipine Besylate: 1 person, 7.14%
  8. Atenolol: 1 person, 7.14%
  9. Ergocalciferol: 1 person, 7.14%
  10. Amlodipine: 1 person, 7.14%

What are other side effects people have besides Hyponatremia? *

  1. Thrombocytopenia (decrease of platelets in blood): 3 people, 21.43%
  2. Blood Creatine Phosphokinase Increased: 2 people, 14.29%
  3. Neuroleptic Malignant Syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents): 2 people, 14.29%
  4. Alanine Aminotransferase Abnormal: 1 person, 7.14%
  5. Antepartum Haemorrhage (bleeding from the vagina during pregnancy from the 24th week): 1 person, 7.14%
  6. Blood Bilirubin Abnormal: 1 person, 7.14%
  7. Agitation (state of anxiety or nervous excitement): 1 person, 7.14%
  8. Blood Creatinine Increased: 1 person, 7.14%
  9. Bradypnea: 1 person, 7.14%
  10. Head Injury: 1 person, 7.14%

What are the existing conditions these people have? *

  1. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 28.57%
  2. Schizoaffective Disorder (a mental disorder characterized by disordered thought): 2 people, 14.29%
  3. Psychotic Disorder: 2 people, 14.29%
  4. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 14.29%
  5. Tremor (trembling or shaking movements in one or more parts of your body): 1 person, 7.14%
  6. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 1 person, 7.14%
  7. High Blood Pressure: 1 person, 7.14%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.14%
  9. Diabetes: 1 person, 7.14%
  10. Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Haloperidol decanoate and have Hyponatremia?

- Check whether Hyponatremia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Haloperidol decanoate:

Hyponatremia treatments and more:

How severe was Hyponatremia and when was it recovered:

Expand to all the drugs that have ingredients of haloperidol decanoate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Haloperidol decanoate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyponatremia:

Browse all the conditions that are associated with Hyponatremia:

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on haloperidol decanoate (the active ingredients of Haloperidol decanoate) and Haloperidol decanoate (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.