Haloperidol and Sleeping difficulty - a phase IV clinical study of FDA data

Summary:

Sleeping difficulty is reported as a side effect among people who take Haloperidol (haloperidol), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Olanzapine, and have Depression.

The phase IV clinical study analyzes which people have Sleeping difficulty when taking Haloperidol. It is created by eHealthMe based on reports of 16,432 people who have side effects when taking Haloperidol from the FDA, and is updated regularly.

What is Haloperidol?

Haloperidol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 16,636 Haloperidol users. Check the latest studies of Haloperidol.

What is Sleeping difficulty?

Sleeping difficulty (difficult sleeping) is found to be associated with 4,222 drugs and 5,350 conditions by eHealthMe. Check the latest studies of Sleeping difficulty.

On Nov, 23, 2025

16,432 people reported to have side effects when taking Haloperidol.
Among them, 367 people (2.23%) have Sleeping difficulty.

Could Haloperidol cause Sleeping difficulty?

Among these 367 people:

How long have people been on Haloperidol when they have Sleeping difficulty? *

What is the gender of people who have Sleeping difficulty when taking Haloperidol? *

female: 42.57 %
male: 57.43 %

What is the age of people who have Sleeping difficulty when taking Haloperidol? *

What are other drugs people take besides Haloperidol? *

What are other side effects people have besides Sleeping difficulty? *

Agitation (state of anxiety or nervous excitement): 98 people, 26.70%
Stress And Anxiety: 97 people, 26.43%
Depression: 67 people, 18.26%
Fatigue (feeling of tiredness): 63 people, 17.17%
Drug Ineffective: 56 people, 15.26%
Confusional State: 51 people, 13.90%
Weakness: 49 people, 13.35%
Aggression: 49 people, 13.35%
Pain: 48 people, 13.08%
Sedation: 47 people, 12.81%

What are the existing conditions these people have? *

Depression: 23 people, 6.27%
Stress And Anxiety: 18 people, 4.90%
Agitation (state of anxiety or nervous excitement): 18 people, 4.90%
Pain: 16 people, 4.36%
Breast Cancer Metastatic: 16 people, 4.36%
Psychotic Disorder: 14 people, 3.81%
Cancer Pain: 12 people, 3.27%
Prostate Cancer: 11 people, 3.00%
Affective Disorder (mental disorder): 10 people, 2.72%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 2.72%

* Approximation only. Some reports may have incomplete information.

Do you take Haloperidol and have Sleeping difficulty?

- Check whether Sleeping difficulty is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Haloperidol:

Haloperidol (16,636 reports)

Common Haloperidol side effects:

Browse all side effects of Haloperidol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sleeping difficulty:

Browse all the drugs that are associated with Sleeping difficulty:

Sleeping difficulty (4,222 drugs)

Common conditions associated with Sleeping difficulty:

Depression aggravated: 17,540 reports
Antidepressant therapy: 17,500 reports
Pain exacerbated: 13,668 reports
Ra: 13,625 reports
Hypnosis and pain: 13,485 reports
Multiple sclerosis aggravated: 12,998 reports
Hypertension: 12,107 reports
Blood pressure - high: 12,061 reports
Anxiety aggravated: 10,449 reports
Feeling uptight: 10,431 reports

Browse all the conditions that are associated with Sleeping difficulty:

Sleeping difficulty (5,350 conditions)

Related publications that referenced our studies

Obayi, O., & Tagbo, N. , "Bilateral Pedal Oedema Associated with Intramuscular Haloperidol–A Rare Observation", International Neuropsychiatric Disease Journal, 2018 Jan .
Obayi, O., & Tagbo, N. , "Bilateral Pedal Oedema Associated with Intramuscular Haloperidol–A Rare Observation", International Neuropsychiatric Disease Journal, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on haloperidol (the active ingredients of Haloperidol) and Haloperidol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.