Harvoni and Irritable bowel syndrome - a phase IV clinical study of FDA data

Summary:

Irritable bowel syndrome is reported as a side effect among people who take Harvoni (ledipasvir; sofosbuvir), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Pegasys, and have Hepatitis c.

The phase IV clinical study analyzes which people have Irritable bowel syndrome when taking Harvoni. It is created by eHealthMe based on reports of 19,802 people who have side effects when taking Harvoni from the FDA, and is updated regularly.

What is Harvoni?

Harvoni has active ingredients of ledipasvir; sofosbuvir. eHealthMe is studying from 19,858 Harvoni users. Check the latest studies of Harvoni.

What is Irritable bowel syndrome?

Irritable bowel syndrome is found to be associated with 1,317 drugs and 2,123 conditions by eHealthMe. Check the latest studies of Irritable bowel syndrome.

On Jul, 17, 2026

19,802 people reported to have side effects when taking Harvoni.
Among them, 20 people (0.1%) have Irritable bowel syndrome.

Could Harvoni cause Irritable bowel syndrome?

Among these 20 people:

How long have people been on Harvoni when they have Irritable bowel syndrome? *

What is the gender of people who have Irritable bowel syndrome when taking Harvoni? *

female: 94.74 %
male: 5.26 %

What is the age of people who have Irritable bowel syndrome when taking Harvoni? *

What are other drugs people take besides Harvoni? *

What are other side effects people have besides Irritable bowel syndrome? *

Insomnia (sleeplessness): 9 people, 45.00%
Fatigue (feeling of tiredness): 9 people, 45.00%
Plantar Fasciitis (painful inflammatory process of the plantar fascia): 8 people, 40.00%
Lung Disorder (lung disease): 8 people, 40.00%
Respiration Abnormal (abnormal breathing process): 8 people, 40.00%
Weight Increased: 8 people, 40.00%
Temperature Regulation Disorder (body is unable to maintain temperature): 7 people, 35.00%
Anger: 7 people, 35.00%
Synovial Cyst (cyst of joint filled with synovial fluid): 7 people, 35.00%
Injury: 7 people, 35.00%

What are the existing conditions these people have? *

Hepatitis C: 12 people, 60.00%
Immunodeficiency Common Variable: 4 people, 20.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 10.00%
Pain: 2 people, 10.00%
Liver Disorder (liver diseases): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Harvoni and have Irritable bowel syndrome?

- Check whether Irritable bowel syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Harvoni:

Harvoni (19,858 reports)

Browse all side effects of Harvoni:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Irritable bowel syndrome:

Irritable bowel syndrome (1,317 drugs)

Browse all the conditions that are associated with Irritable bowel syndrome:

Irritable bowel syndrome (2,123 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ledipasvir; sofosbuvir (the active ingredients of Harvoni) and Harvoni (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.