Heparin and Neurological decompensation - a phase IV clinical study of FDA data

Summary:

Neurological decompensation is reported as a side effect among people who take Heparin (heparin sodium), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Aspirin, and have Thrombosis.

The phase IV clinical study analyzes which people have Neurological decompensation when taking Heparin. It is created by eHealthMe based on reports of 91,860 people who have side effects when taking Heparin from the FDA, and is updated regularly.

What is Heparin?

Heparin has active ingredients of heparin sodium. It is often used in blood clots. eHealthMe is studying from 92,141 Heparin users. Check the latest studies of Heparin.

What is Neurological decompensation?

Neurological decompensation (inability of brain to maintain proper function) is found to be associated with 256 drugs and 451 conditions by eHealthMe. Check the latest studies of Neurological decompensation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

91,860 people reported to have side effects when taking Heparin.
Among them, 45 people (0.05%) have Neurological decompensation.

Could Heparin cause Neurological decompensation?

Among these 45 people:

How long have people been on Heparin when they have Neurological decompensation? *

  • < 1 month: 40 %
  • 1 - 6 months: 60 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Neurological decompensation when taking Heparin? *

  • female: 40 %
  • male: 60 %

What is the age of people who have Neurological decompensation when taking Heparin? *

  • 0-1: 0.0 %
  • 2-9: 8.33 %
  • 10-19: 2.78 %
  • 20-29: 0.0 %
  • 30-39: 2.78 %
  • 40-49: 16.67 %
  • 50-59: 8.33 %
  • 60+: 61.11 %

What are other drugs people take besides Heparin? *

  1. Clopidogrel: 6 people, 13.33%
  2. Aspirin: 6 people, 13.33%
  3. Zyrtec: 4 people, 8.89%
  4. Ondansetron: 3 people, 6.67%
  5. Pantoprazole: 3 people, 6.67%
  6. Keppra: 3 people, 6.67%
  7. Lasix: 3 people, 6.67%
  8. Levofloxacin: 3 people, 6.67%
  9. Decadron: 3 people, 6.67%
  10. Methylprednisolone: 3 people, 6.67%

What are other side effects people have besides Neurological decompensation? *

  1. Cerebral Haemorrhage (bleeding within the brain): 8 people, 17.78%
  2. Death: 8 people, 17.78%
  3. Hydrocephalus (water on the brain): 5 people, 11.11%
  4. Acute Kidney Failure: 5 people, 11.11%
  5. Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 5 people, 11.11%
  6. Headache (pain in head): 5 people, 11.11%
  7. Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 5 people, 11.11%
  8. Subdural Haematoma (blood collects between the skull and the surface of the brain): 5 people, 11.11%
  9. Areflexia (absence of a reflex): 4 people, 8.89%
  10. Brain Herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull): 4 people, 8.89%

What are the existing conditions these people have? *

  1. Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 8.89%
  2. Pulmonary Embolism (blockage of the main artery of the lung): 3 people, 6.67%
  3. Ischaemic Stroke (stroke; caused by an interruption in the flow of blood to the brain): 3 people, 6.67%
  4. High Blood Pressure: 2 people, 4.44%
  5. Fabry's Disease (build up of a particular type of fat, called globotriaosylceramide, in the body's cells): 2 people, 4.44%
  6. Depression: 2 people, 4.44%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.44%
  8. Immunodeficiency Disorders: 2 people, 4.44%
  9. Insomnia (sleeplessness): 2 people, 4.44%
  10. Cholestasis (a condition where bile cannot flow from the liver to the duodenum): 2 people, 4.44%

* Approximation only. Some reports may have incomplete information.

Do you take Heparin and have Neurological decompensation?

- Check whether Neurological decompensation is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Heparin:

Neurological decompensation treatments and more:

How severe was Neurological decompensation and when was it recovered:

Expand to all the drugs that have ingredients of heparin sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Heparin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neurological decompensation:

Browse all the conditions that are associated with Neurological decompensation:


How the study uses the data?

The study uses data from the FDA. It is based on heparin sodium (the active ingredients of Heparin) and Heparin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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