Hetlioz and Throat irritation - a phase IV clinical study of FDA data

Summary:

Throat irritation is reported as a side effect among people who take Hetlioz (tasimelteon), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Lasix, and have Circadian rhythm sleep disorder.

The phase IV clinical study analyzes which people have Throat irritation when taking Hetlioz. It is created by eHealthMe based on reports of 7,418 people who have side effects when taking Hetlioz from the FDA, and is updated regularly.

What is Hetlioz?

Hetlioz has active ingredients of tasimelteon. eHealthMe is studying from 7,418 Hetlioz users. Check the latest studies of Hetlioz.

What is Throat irritation?

Throat irritation is found to be associated with 1,420 drugs and 1,504 conditions by eHealthMe. Check the latest studies of Throat irritation.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

7,418 people reported to have side effects when taking Hetlioz.
Among them, 22 people (0.3%) have Throat irritation.

Among these 22 people:

How long have people been on Hetlioz when they have Throat irritation? *

What is the gender of people who have Throat irritation when taking Hetlioz? *

female: 59.09 %
male: 40.91 %

What is the age of people who have Throat irritation when taking Hetlioz? *

What are other drugs people take besides Hetlioz? *

What are other side effects people have besides Throat irritation? *

Hypersensitivity: 5 people, 22.73%
Cough: 4 people, 18.18%
Dyspnea (difficult or laboured breathing): 3 people, 13.64%
Hoarseness Or Changing Voice: 3 people, 13.64%
Headache (pain in head): 2 people, 9.09%
Swallowing Difficulty: 2 people, 9.09%
Sleep Disorder: 2 people, 9.09%
Rashes (redness): 2 people, 9.09%
Oesophageal Disorder (disease of oesophagus): 2 people, 9.09%
Dry Mouth: 2 people, 9.09%

What are the existing conditions these people have? *

Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep): 12 people, 54.55%
Blindness: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Hetlioz and have Throat irritation?

- Check whether Throat irritation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hetlioz:

Hetlioz (7,418 reports)

Browse all side effects of Hetlioz:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Throat irritation:

Throat irritation (1,420 drugs)

Browse all the conditions that are associated with Throat irritation:

Throat irritation (1,504 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tasimelteon (the active ingredients of Hetlioz) and Hetlioz (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.