Hiprex and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Hiprex (methenamine hippurate), especially for people who are male, 60+ old, have been taking the drug for 2 - 5 years also take Acetaminophen, and have High blood pressure.

The phase IV clinical study analyzes which people have Constipation when taking Hiprex. It is created by eHealthMe based on reports of 812 people who have side effects when taking Hiprex from the FDA, and is updated regularly.

What is Hiprex?

Hiprex has active ingredients of methenamine hippurate. It is often used in urinary tract infection. eHealthMe is studying from 900 Hiprex users. Check the latest studies of Hiprex.

What is Constipation?

Constipation is found to be associated with 3,004 drugs and 4,609 conditions by eHealthMe. Check the latest studies of Constipation.

On Jul, 09, 2026

812 people reported to have side effects when taking Hiprex.
Among them, 17 people (2.09%) have Constipation.

Among these 17 people:

How long have people been on Hiprex when they have Constipation? *

What is the gender of people who have Constipation when taking Hiprex? *

female: 43.75 %
male: 56.25 %

What is the age of people who have Constipation when taking Hiprex? *

What are other drugs people take besides Hiprex? *

What are other side effects people have besides Constipation? *

Diarrhea: 6 people, 35.29%
Nausea (feeling of having an urge to vomit): 4 people, 23.53%
Nausea And Vomiting: 4 people, 23.53%
Fever: 3 people, 17.65%
Yellow Skin: 2 people, 11.76%
Fatigue (feeling of tiredness): 2 people, 11.76%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 2 people, 11.76%
Haemorrhage (bleeding): 2 people, 11.76%
Weakness: 2 people, 11.76%
Full Blood Count Decreased: 2 people, 11.76%

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 11.76%
Indigestion: 2 people, 11.76%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 11.76%
Rectal Cancer (cancer of rectum): 2 people, 11.76%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 11.76%
Pain: 2 people, 11.76%
High Blood Cholesterol: 2 people, 11.76%
High Blood Pressure: 2 people, 11.76%
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 1 person, 5.88%
Gastritis (inflammation of stomach): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Hiprex and have Constipation?

- Check whether Constipation is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hiprex:

Hiprex (900 reports)

Constipation treatments and more:

Constipation (337,879 reports)

Browse all side effects of Hiprex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,004 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,609 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methenamine hippurate (the active ingredients of Hiprex) and Hiprex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.