Humalog and Fibula fracture - a phase IV clinical study of FDA data

Summary:

Fibula fracture is reported as a side effect among people who take Humalog (insulin lispro recombinant), especially for people who are female, 50-59 old, also take Lantus, and have Osteoporosis.

The phase IV clinical study analyzes which people have Fibula fracture when taking Humalog. It is created by eHealthMe based on reports of 136,521 people who have side effects when taking Humalog from the FDA, and is updated regularly.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

What is Fibula fracture?

Fibula fracture is found to be associated with 561 drugs and 581 conditions by eHealthMe. Check the latest studies of Fibula fracture.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

136,521 people reported to have side effects when taking Humalog.
Among them, 41 people (0.03%) have Fibula fracture.

$Could Humalog cause Fibula fracture?$

Among these 41 people:

What is the gender of people who have Fibula fracture when taking Humalog? *

female: 74.36 %
male: 25.64 %

What is the age of people who have Fibula fracture when taking Humalog? *

What are other drugs people take besides Humalog? *

What are other side effects people have besides Fibula fracture? *

Fall: 27 people, 65.85%
Tibia Fracture (fracture of lower leg bone): 25 people, 60.98%
Ankle Fracture: 12 people, 29.27%
Drug Ineffective: 11 people, 26.83%
Weight Decreased: 10 people, 24.39%
Dizziness: 10 people, 24.39%
Pain: 9 people, 21.95%
Foot Fracture: 9 people, 21.95%
Injection Site Reaction: 8 people, 19.51%
Injection Site Swelling: 8 people, 19.51%

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 8 people, 19.51%
Temporal Lobe Epilepsy (a term that refers to a condition where seizures are generated in the portion of the brain called the temporal lobe): 7 people, 17.07%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 4.88%
Hepatitis C: 2 people, 4.88%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 4.88%
High Blood Pressure: 2 people, 4.88%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 4.88%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 2.44%
Fever: 1 person, 2.44%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 2.44%

* Approximation only. Some reports may have incomplete information.

Do you take Humalog and have Fibula fracture?

- Check whether Fibula fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Humalog:

Humalog (137,127 reports)

Fibula fracture treatments and more:

Fibula fracture (4,153 reports)

Browse all side effects of Humalog:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fibula fracture:

Fibula fracture (561 drugs)

Browse all the conditions that are associated with Fibula fracture:

Fibula fracture (581 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on insulin lispro recombinant (the active ingredients of Humalog) and Humalog (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.