Humira and Drooling - a phase IV clinical study of FDA data

Summary:

Drooling is reported as a side effect among people who take Humira (adalimumab), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Paracetamol, and have Depression.

The phase IV clinical study analyzes which people have Drooling when taking Humira. It is created by eHealthMe based on reports of 758,421 people who have side effects when taking Humira from the FDA, and is updated regularly.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,396 Humira users. Check the latest studies of Humira.

What is Drooling?

Drooling (drop saliva uncontrollably from the mouth) is found to be associated with 497 drugs and 941 conditions by eHealthMe. Check the latest studies of Drooling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

758,421 people reported to have side effects when taking Humira.
Among them, 69 people (0.01%) have Drooling.

Could Humira cause Drooling?

Among these 69 people:

How long have people been on Humira when they have Drooling? *

  • < 1 month: 20 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 5 %
  • 1 - 2 years: 20 %
  • 2 - 5 years: 10 %
  • 5 - 10 years: 20 %
  • 10+ years: 0.0 %

What is the gender of people who have Drooling when taking Humira? *

  • female: 63.77 %
  • male: 36.23 %

What is the age of people who have Drooling when taking Humira? *

  • 0-1: 0.0 %
  • 2-9: 2.04 %
  • 10-19: 0.0 %
  • 20-29: 18.37 %
  • 30-39: 14.29 %
  • 40-49: 12.24 %
  • 50-59: 16.33 %
  • 60+: 36.73 %

What are other drugs people take besides Humira? *

  1. Paracetamol: 7 people, 10.14%
  2. Potassium: 6 people, 8.70%
  3. Calcium: 6 people, 8.70%
  4. Amlodipine: 5 people, 7.25%
  5. Vitamin D: 5 people, 7.25%
  6. Ativan: 4 people, 5.80%
  7. Remicade: 4 people, 5.80%
  8. Celebrex: 4 people, 5.80%
  9. Xanax: 4 people, 5.80%
  10. Protonix: 3 people, 4.35%

What are other side effects people have besides Drooling? *

  1. Speech Impairment (Adult) (inability to speak (adult)): 20 people, 28.99%
  2. Hypoaesthesia (reduced sense of touch or sensation): 13 people, 18.84%
  3. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 12 people, 17.39%
  4. Joint Pain: 11 people, 15.94%
  5. Feeling Abnormal: 11 people, 15.94%
  6. Memory Loss: 11 people, 15.94%
  7. Dizziness: 10 people, 14.49%
  8. Speech Disorder: 10 people, 14.49%
  9. Fall: 10 people, 14.49%
  10. Urinary Tract Infection: 9 people, 13.04%

What are the existing conditions these people have? *

  1. Depression: 10 people, 14.49%
  2. Pain: 9 people, 13.04%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 9 people, 13.04%
  4. High Blood Pressure: 8 people, 11.59%
  5. Fibromyalgia (a long-term condition which causes pain all over the body): 8 people, 11.59%
  6. Psoriasis (immune-mediated disease that affects the skin): 8 people, 11.59%
  7. Ankylosing Spondylitis (type of arthritis affecting the spine): 8 people, 11.59%
  8. Hidradenitis (chronic disease of a type of sweat gland): 7 people, 10.14%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.70%
  10. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 5 people, 7.25%

* Approximation only. Some reports may have incomplete information.

Do you take Humira and have Drooling?

- Check whether Drooling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Humira:

Drooling treatments and more:

How severe was Drooling and when was it recovered:

Expand to all the drugs that have ingredients of adalimumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Drooling:

Browse all the conditions that are associated with Drooling:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: