Humira and Hyperthyroid - a phase IV clinical study of FDA data

Summary:

Hyperthyroid is reported as a side effect among people who take Humira (adalimumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Methotrexate, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperthyroid when taking Humira. It is created by eHealthMe based on reports of 758,421 people who have side effects when taking Humira from the FDA, and is updated regularly.

What is Humira?

Humira has active ingredients of adalimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 761,389 Humira users. Check the latest studies of Humira.

What is Hyperthyroid?

Hyperthyroid is found to be associated with 1,145 drugs and 1,397 conditions by eHealthMe. Check the latest studies of Hyperthyroid.



On Jul, 30, 2025

758,421 people reported to have side effects when taking Humira.
Among them, 333 people (0.04%) have Hyperthyroid.

Could Humira cause Hyperthyroid?

Among these 333 people:

How long have people been on Humira when they have Hyperthyroid? *

  • < 1 month: 19.78 %
  • 1 - 6 months: 19.78 %
  • 6 - 12 months: 10.99 %
  • 1 - 2 years: 18.68 %
  • 2 - 5 years: 18.68 %
  • 5 - 10 years: 10.99 %
  • 10+ years: 1.1 %

What is the gender of people who have Hyperthyroid when taking Humira? *

  • female: 76.76 %
  • male: 23.24 %

What is the age of people who have Hyperthyroid when taking Humira? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.87 %
  • 20-29: 4.8 %
  • 30-39: 6.99 %
  • 40-49: 15.72 %
  • 50-59: 30.57 %
  • 60+: 41.05 %

What are other drugs people take besides Humira? *

  1. Methotrexate: 36 people, 10.81%
  2. Amlodipine: 22 people, 6.61%
  3. Folic Acid: 18 people, 5.41%
  4. Omeprazole: 17 people, 5.11%
  5. Prednisolone: 17 people, 5.11%
  6. Sulfasalazine: 15 people, 4.50%
  7. Synthroid: 15 people, 4.50%
  8. Prednisone: 14 people, 4.20%
  9. Flonase: 11 people, 3.30%
  10. Vitamin D3: 11 people, 3.30%

What are other side effects people have besides Hyperthyroid? *

  1. Joint Pain: 40 people, 12.01%
  2. Drug Ineffective: 37 people, 11.11%
  3. High Blood Pressure: 35 people, 10.51%
  4. Pain: 35 people, 10.51%
  5. Abdominal Pain: 34 people, 10.21%
  6. Fatigue (feeling of tiredness): 34 people, 10.21%
  7. Diarrhea: 31 people, 9.31%
  8. Insomnia (sleeplessness): 31 people, 9.31%
  9. Pneumonia: 31 people, 9.31%
  10. Stress And Anxiety: 28 people, 8.41%

What are the existing conditions these people have? *

  1. Psoriasis (immune-mediated disease that affects the skin): 41 people, 12.31%
  2. High Blood Pressure: 41 people, 12.31%
  3. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 36 people, 10.81%
  4. Ankylosing Spondylitis (type of arthritis affecting the spine): 33 people, 9.91%
  5. Pain: 29 people, 8.71%
  6. High Blood Cholesterol: 22 people, 6.61%
  7. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 16 people, 4.80%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 14 people, 4.20%
  9. Hidradenitis (chronic disease of a type of sweat gland): 12 people, 3.60%
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 3.30%

* Approximation only. Some reports may have incomplete information.

Do you take Humira and have Hyperthyroid?

- Check whether Hyperthyroid is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Humira:

Hyperthyroid treatments and more:

How severe was Hyperthyroid and when was it recovered:

Expand to all the drugs that have ingredients of adalimumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Humira side effects:

Browse all side effects of Humira:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Hyperthyroid:

Browse all the drugs that are associated with Hyperthyroid:

Common conditions associated with Hyperthyroid:

Browse all the conditions that are associated with Hyperthyroid:

Drugs similar to Humira and Hyperthyroid :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on adalimumab (the active ingredients of Humira) and Humira (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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