Humulin r and Aortic valve incompetence - a phase IV clinical study of FDA data

Summary:

Aortic valve incompetence is reported as a side effect among people who take Humulin r (insulin recombinant human), especially for people who are male, 50-59 old, also take Digoxin, and have Panic disorder.

The phase IV clinical study analyzes which people have Aortic valve incompetence when taking Humulin r. It is created by eHealthMe based on reports of 22,077 people who have side effects when taking Humulin r from the FDA, and is updated regularly.

What is Humulin r?

Humulin r has active ingredients of insulin recombinant human. It is often used in type 1 diabetes. eHealthMe is studying from 22,147 Humulin r users. Check the latest studies of Humulin r.

What is Aortic valve incompetence?

Aortic valve incompetence is found to be associated with 914 drugs and 881 conditions by eHealthMe. Check the latest studies of Aortic valve incompetence.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

22,077 people reported to have side effects when taking Humulin r.
Among them, 19 people (0.09%) have Aortic valve incompetence.

Could Humulin r cause Aortic valve incompetence?

Among these 19 people:

What is the gender of people who have Aortic valve incompetence when taking Humulin r? *

female: 10.53 %
male: 89.47 %

What is the age of people who have Aortic valve incompetence when taking Humulin r? *

What are other drugs people take besides Humulin r? *

What are other side effects people have besides Aortic valve incompetence? *

Tricuspid Valve Incompetence (inefficient heart valve): 11 people, 57.89%
Arrhythmias (irregular heartbeat): 9 people, 47.37%
Cardiac Murmur (an heart sound in valve abnormality): 8 people, 42.11%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 8 people, 42.11%
Pain In Extremity: 8 people, 42.11%
Left Ventricular Hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart): 8 people, 42.11%
Joint Pain: 8 people, 42.11%
Weakness: 8 people, 42.11%
Drug Exposure During Pregnancy: 7 people, 36.84%
Swallowing Difficulty: 7 people, 36.84%

What are the existing conditions these people have? *

Panic Disorder: 7 people, 36.84%
Multiple Myeloma (cancer of the plasma cells): 5 people, 26.32%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 5.26%
Cardiac Failure Congestive: 1 person, 5.26%
Cardiac Disorder: 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Humulin r and have Aortic valve incompetence?

- Check whether Aortic valve incompetence is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Humulin r:

Humulin r (22,147 reports)

Browse all side effects of Humulin r:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aortic valve incompetence:

Aortic valve incompetence (914 drugs)

Browse all the conditions that are associated with Aortic valve incompetence:

Aortic valve incompetence (881 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on insulin recombinant human (the active ingredients of Humulin r) and Humulin r (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.