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Humulin r and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Humulin r (insulin recombinant human), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Furosemide, and have Restless leg syndrome.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Humulin r. It is created by eHealthMe based on reports of 22,077 people who have side effects when taking Humulin r from the FDA, and is updated regularly.

What is Humulin r?

Humulin r has active ingredients of insulin recombinant human. It is often used in type 1 diabetes. eHealthMe is studying from 22,147 Humulin r users. Check the latest studies of Humulin r.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,042 drugs and 1,783 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.



On Jul, 14, 2026

22,077 people reported to have side effects when taking Humulin r.
Among them, 16 people (0.07%) have Clostridium difficile colitis.

Could Humulin r cause Clostridium difficile colitis?

Among these 16 people:

How long have people been on Humulin r when they have Clostridium difficile colitis? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Clostridium difficile colitis when taking Humulin r? *

  • female: 43.75 %
  • male: 56.25 %

What is the age of people who have Clostridium difficile colitis when taking Humulin r? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 12.5 %
  • 50-59: 12.5 %
  • 60+: 75.0 %

What are other drugs people take besides Humulin r? *

  1. Furosemide: 7 people, 43.75%
  2. Zocor: 5 people, 31.25%
  3. Leucovorin Calcium: 5 people, 31.25%
  4. Fosamax: 5 people, 31.25%
  5. Prednisone: 5 people, 31.25%
  6. Fluorouracil: 5 people, 31.25%
  7. Toprol-Xl: 5 people, 31.25%
  8. Cardura: 5 people, 31.25%
  9. Lovenox: 5 people, 31.25%
  10. Aspirin: 5 people, 31.25%

What are other side effects people have besides Clostridium difficile colitis? *

  1. Hypotension (abnormally low blood pressure): 7 people, 43.75%
  2. Pleural Effusion (water on the lungs): 6 people, 37.50%
  3. Pneumonia: 6 people, 37.50%
  4. Nausea And Vomiting: 5 people, 31.25%
  5. Weight Decreased: 4 people, 25.00%
  6. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 25.00%
  7. Nausea (feeling of having an urge to vomit): 4 people, 25.00%
  8. Respiratory Distress (difficulty in breathing): 3 people, 18.75%
  9. Weakness: 3 people, 18.75%
  10. Fatigue (feeling of tiredness): 3 people, 18.75%

What are the existing conditions these people have? *

  1. Urination - Excessive Volume: 5 people, 31.25%
  2. Prostatic Disorder: 5 people, 31.25%
  3. Colon Cancer: 5 people, 31.25%
  4. High Blood Cholesterol: 5 people, 31.25%
  5. Osteoporosis (bones weak and more likely to break): 5 people, 31.25%
  6. Restless Leg Syndrome (a powerful urge to move your legs): 5 people, 31.25%
  7. Pain: 4 people, 25.00%
  8. Stress And Anxiety: 4 people, 25.00%
  9. Paroxysmal Nocturnal Haemoglobinuria (haemoglobin in the urine): 3 people, 18.75%
  10. Rosacea (a skin condition that causes facial redness): 3 people, 18.75%

* Approximation only. Some reports may have incomplete information.

Do you take Humulin r and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Humulin r:

Clostridium difficile colitis treatments and more:

How severe was Clostridium difficile colitis and when was it recovered:

Expand to all the drugs that have ingredients of insulin recombinant human:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Humulin r:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Browse all the conditions that are associated with Clostridium difficile colitis:


How the study uses the data?

The study uses data from the FDA. It is based on insulin recombinant human (the active ingredients of Humulin r) and Humulin r (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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