Hycodan and Constipation - a phase IV clinical study of FDA data

Summary:

Constipation is reported as a side effect among people who take Hycodan (homatropine methylbromide; hydrocodone bitartrate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Oxycontin, and have Pain.

The phase IV clinical study analyzes which people have Constipation when taking Hycodan. It is created by eHealthMe based on reports of 713 people who have side effects when taking Hycodan from the FDA, and is updated regularly.

What is Hycodan?

Hycodan has active ingredients of homatropine methylbromide; hydrocodone bitartrate. It is often used in cough. eHealthMe is studying from 769 Hycodan users. Check the latest studies of Hycodan.

What is Constipation?

Constipation is found to be associated with 3,003 drugs and 4,577 conditions by eHealthMe. Check the latest studies of Constipation.

On Nov, 25, 2025

713 people reported to have side effects when taking Hycodan.
Among them, 26 people (3.65%) have Constipation.

Among these 26 people:

How long have people been on Hycodan when they have Constipation? *

What is the gender of people who have Constipation when taking Hycodan? *

female: 60 %
male: 40 %

What is the age of people who have Constipation when taking Hycodan? *

What are other drugs people take besides Hycodan? *

What are other side effects people have besides Constipation? *

Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 8 people, 30.77%
Stress And Anxiety: 8 people, 30.77%
Hyperhidrosis (abnormally increased sweating): 8 people, 30.77%
Drug Dependence: 8 people, 30.77%
Depression: 8 people, 30.77%
Neuropathy Peripheral (surface nerve damage): 7 people, 26.92%
Pain In Extremity: 7 people, 26.92%
Abdominal Pain: 7 people, 26.92%
Confusion: 7 people, 26.92%
Weakness: 7 people, 26.92%

What are the existing conditions these people have? *

Pain: 14 people, 53.85%
Multiple Myeloma (cancer of the plasma cells): 6 people, 23.08%
Headache (pain in head): 6 people, 23.08%
Dry Eyes (lack of adequate tears): 4 people, 15.38%
Sleep Disorder: 4 people, 15.38%
High Blood Pressure: 2 people, 7.69%
Nausea (feeling of having an urge to vomit): 2 people, 7.69%
Stress And Anxiety: 2 people, 7.69%
Dizziness: 2 people, 7.69%
Depression: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Hycodan and have Constipation?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hycodan:

Hycodan (769 reports)

Constipation treatments and more:

Constipation (337,856 reports)

How severe was Constipation and when was it recovered:

Constipation in Hycodan

Expand to all the drugs that have ingredients of homatropine methylbromide; hydrocodone bitartrate:

Constipation and drugs with ingredients of homatropine methylbromide; hydrocodone bitartrate (1,226 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hycodan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Constipation:

Constipation (3,003 drugs)

Browse all the conditions that are associated with Constipation:

Constipation (4,577 conditions)

Drugs similar to Hycodan and Constipation :

How the study uses the data?

The study uses data from the FDA. It is based on homatropine methylbromide; hydrocodone bitartrate (the active ingredients of Hycodan) and Hycodan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.