Hydramine and Biliary tract disorder - a phase IV clinical study of FDA data

Summary:

Biliary tract disorder is reported as a side effect among people who take Hydramine (diphenhydramine hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Biliary tract disorder when taking Hydramine. It is created by eHealthMe based on reports of 113,450 people who have side effects when taking Hydramine from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Biliary tract disorder?

Biliary tract disorder is found to be associated with 285 drugs and 401 conditions by eHealthMe. Check the latest studies of Biliary tract disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

113,450 people reported to have side effects when taking Hydramine.
Among them, 17 people (0.01%) have Biliary tract disorder.

Could Hydramine cause Biliary tract disorder?

Among these 17 people:

How long have people been on Hydramine when they have Biliary tract disorder? *

What is the gender of people who have Biliary tract disorder when taking Hydramine? *

female: 41.18 %
male: 58.82 %

What is the age of people who have Biliary tract disorder when taking Hydramine? *

What are other drugs people take besides Hydramine? *

What are other side effects people have besides Biliary tract disorder? *

Respiratory Tract Infection: 8 people, 47.06%
Fever: 6 people, 35.29%
Diarrhea: 6 people, 35.29%
Fall: 5 people, 29.41%
Nausea (feeling of having an urge to vomit): 5 people, 29.41%
Head Injury: 4 people, 23.53%
Pneumonia: 4 people, 23.53%
Respiration Abnormal (abnormal breathing process): 4 people, 23.53%
Cyst (a closed sac): 4 people, 23.53%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 4 people, 23.53%

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 5 people, 29.41%
Lennox-Gastaut Syndrome (epilepsy characterized by frequent seizures and different seizure types): 4 people, 23.53%
Liver Transplant Rejection (failure of liver transplant): 2 people, 11.76%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.88%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.88%
Immunodeficiency Disorders: 1 person, 5.88%
Gastric Disorder (disease of stomach): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Hydramine and have Biliary tract disorder?

- Check whether Biliary tract disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydramine:

Hydramine (114,900 reports)

Browse all side effects of Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Biliary tract disorder:

Biliary tract disorder (285 drugs)

Browse all the conditions that are associated with Biliary tract disorder:

Biliary tract disorder (401 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Hydramine) and Hydramine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.