Hydramine and Panic attack - a phase IV clinical study of FDA data

Summary:

Panic attack is reported as a side effect among people who take Hydramine (diphenhydramine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Acetaminophen, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Panic attack when taking Hydramine. It is created by eHealthMe based on reports of 113,450 people who have side effects when taking Hydramine from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Panic attack?

Panic attack is found to be associated with 2,419 drugs and 2,081 conditions by eHealthMe. Check the latest studies of Panic attack.

On Apr, 14, 2026

113,450 people reported to have side effects when taking Hydramine.
Among them, 328 people (0.29%) have Panic attack.

Among these 328 people:

How long have people been on Hydramine when they have Panic attack? *

What is the gender of people who have Panic attack when taking Hydramine? *

female: 85.49 %
male: 14.51 %

What is the age of people who have Panic attack when taking Hydramine? *

What are other drugs people take besides Hydramine? *

What are other side effects people have besides Panic attack? *

Stress And Anxiety: 191 people, 58.23%
Fatigue (feeling of tiredness): 139 people, 42.38%
Nausea (feeling of having an urge to vomit): 134 people, 40.85%
Joint Pain: 134 people, 40.85%
Malaise (a feeling of general discomfort or uneasiness): 127 people, 38.72%
Headache (pain in head): 125 people, 38.11%
Dyspnea (difficult or laboured breathing): 124 people, 37.80%
Pain: 123 people, 37.50%
Fever: 104 people, 31.71%
Back Pain: 104 people, 31.71%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 88 people, 26.83%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 43 people, 13.11%
Immunodeficiency Common Variable: 34 people, 10.37%
Pain: 32 people, 9.76%
Primary Immunodeficiency Syndrome: 23 people, 7.01%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 22 people, 6.71%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 5.79%
High Blood Pressure: 15 people, 4.57%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 15 people, 4.57%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 13 people, 3.96%

* Approximation only. Some reports may have incomplete information.

Do you take Hydramine and have Panic attack?

- Check whether Panic attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydramine:

Hydramine (114,900 reports)

Panic attack treatments and more:

Panic attack (65,704 reports)

Browse all side effects of Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Panic attack:

Panic attack (2,419 drugs)

Browse all the conditions that are associated with Panic attack:

Panic attack (2,081 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Hydramine) and Hydramine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.