Hydramine and Resorption bone increased - a phase IV clinical study of FDA data

Summary:

Resorption bone increased is reported as a side effect among people who take Hydramine (diphenhydramine hydrochloride), especially for people who are female, 60+ old, also take Cephalexin, and have Immunodeficiency common variable.

The phase IV clinical study analyzes which people have Resorption bone increased when taking Hydramine. It is created by eHealthMe based on reports of 113,450 people who have side effects when taking Hydramine from the FDA, and is updated regularly.

What is Hydramine?

Hydramine has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. eHealthMe is studying from 114,900 Hydramine users. Check the latest studies of Hydramine.

What is Resorption bone increased?

Resorption bone increased is found to be associated with 236 drugs and 262 conditions by eHealthMe. Check the latest studies of Resorption bone increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

113,450 people reported to have side effects when taking Hydramine.
Among them, 12 people (0.01%) have Resorption bone increased.

Could Hydramine cause Resorption bone increased?

Among these 12 people:

What is the gender of people who have Resorption bone increased when taking Hydramine? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Resorption bone increased when taking Hydramine? *

What are other drugs people take besides Hydramine? *

Atenolol: 10 people, 83.33%
Cephalexin: 10 people, 83.33%
Zometa: 6 people, 50.00%
Methotrexate: 6 people, 50.00%
Cyclobenzaprine Hydrochloride: 6 people, 50.00%
Gabapentin: 6 people, 50.00%
Acetaminophen: 6 people, 50.00%
Zetia: 6 people, 50.00%
Dapsone: 5 people, 41.67%
Clinoril: 5 people, 41.67%

What are other side effects people have besides Resorption bone increased? *

Pain: 11 people, 91.67%
Joint Dislocation (a joint position is changed from normal position): 10 people, 83.33%
Diarrhea: 8 people, 66.67%
Fall: 8 people, 66.67%
Abdominal Pain: 7 people, 58.33%
Fatigue (feeling of tiredness): 7 people, 58.33%
Back Pain: 7 people, 58.33%
Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 7 people, 58.33%
General Physical Health Deterioration (weak health status): 6 people, 50.00%
Dental Caries: 6 people, 50.00%

What are the existing conditions these people have? *

Primary Immunodeficiency Syndrome: 5 people, 41.67%
Osteoporosis (bones weak and more likely to break): 5 people, 41.67%
Immunodeficiency Common Variable: 5 people, 41.67%
Metastases To Bone (cancer spreads to bone): 1 person, 8.33%
Breast Cancer: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Hydramine and have Resorption bone increased?

- Check whether Resorption bone increased is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydramine:

Hydramine (114,900 reports)

Browse all side effects of Hydramine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Resorption bone increased:

Resorption bone increased (236 drugs)

Browse all the conditions that are associated with Resorption bone increased:

Resorption bone increased (262 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on diphenhydramine hydrochloride (the active ingredients of Hydramine) and Hydramine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.