Hydrea and Urinary retention - a phase IV clinical study of FDA data

Summary:

Urinary retention is reported as a side effect among people who take Hydrea (hydroxyurea), especially for people who are female, 60+ old, also take Compazine, and have Acute myeloid leukaemia.

The phase IV clinical study analyzes which people have Urinary retention when taking Hydrea. It is created by eHealthMe based on reports of 8,922 people who have side effects when taking Hydrea from the FDA, and is updated regularly.

What is Hydrea?

Hydrea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 9,083 Hydrea users. Check the latest studies of Hydrea.

What is Urinary retention?

Urinary retention (the inability to completely or partially empty the bladder) is found to be associated with 1,567 drugs and 1,742 conditions by eHealthMe. Check the latest studies of Urinary retention.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

8,922 people reported to have side effects when taking Hydrea.
Among them, 13 people (0.15%) have Urinary retention.

Among these 13 people:

What is the gender of people who have Urinary retention when taking Hydrea? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Urinary retention when taking Hydrea? *

What are other drugs people take besides Hydrea? *

What are other side effects people have besides Urinary retention? *

Fall: 5 people, 38.46%
Oedema Peripheral (superficial swelling): 5 people, 38.46%
Dehydration (dryness resulting from the removal of water): 5 people, 38.46%
High Blood Pressure: 5 people, 38.46%
Confusion: 5 people, 38.46%
Nausea (feeling of having an urge to vomit): 5 people, 38.46%
Kidney Infection (Pyelonephritis): 4 people, 30.77%
Sepsis (a severe blood infection that can lead to organ failure and death): 4 people, 30.77%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 4 people, 30.77%
Hypokalemia (low potassium): 4 people, 30.77%

What are the existing conditions these people have? *

Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 15.38%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 15.38%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 7.69%
Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 1 person, 7.69%
Polycythaemia (proportion of blood volume that is occupied by red blood cells increases): 1 person, 7.69%
Pain: 1 person, 7.69%
Oedema Peripheral (superficial swelling): 1 person, 7.69%
Chronic Kidney Disease: 1 person, 7.69%
Anaemia (lack of blood): 1 person, 7.69%
Agitation (state of anxiety or nervous excitement): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrea and have Urinary retention?

- Check whether Urinary retention is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrea:

Hydrea (9,083 reports)

Browse all side effects of Hydrea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Urinary retention:

Urinary retention (1,567 drugs)

Browse all the conditions that are associated with Urinary retention:

Urinary retention (1,742 conditions)

Related publications that referenced our studies

Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .
Schattner A, Al-Bewerat A, "Levetiracetam (Keppra), urinary retention and literature search", A fatty cause of renal failure; what is your diagnosis?, 2016 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on hydroxyurea (the active ingredients of Hydrea) and Hydrea (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.