Hydrochlorothiazide and Biliary tract disorder - a phase IV clinical study of FDA data

Summary:

Biliary tract disorder is reported as a side effect among people who take Hydrochlorothiazide (hydrochlorothiazide), especially for people who are female, 60+ old, have been taking the drug for 6 - 12 months also take Prilosec, and have Carcinoid syndrome.

The phase IV clinical study analyzes which people have Biliary tract disorder when taking Hydrochlorothiazide. It is created by eHealthMe based on reports of 177,544 people who have side effects when taking Hydrochlorothiazide from the FDA, and is updated regularly.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

What is Biliary tract disorder?

Biliary tract disorder is found to be associated with 286 drugs and 400 conditions by eHealthMe. Check the latest studies of Biliary tract disorder.



On Jul, 13, 2026

177,544 people reported to have side effects when taking Hydrochlorothiazide.
Among them, 45 people (0.03%) have Biliary tract disorder.

Could Hydrochlorothiazide cause Biliary tract disorder?

Among these 45 people:

How long have people been on Hydrochlorothiazide when they have Biliary tract disorder? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 100 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Biliary tract disorder when taking Hydrochlorothiazide? *

  • female: 53.33 %
  • male: 46.67 %

What is the age of people who have Biliary tract disorder when taking Hydrochlorothiazide? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 2.7 %
  • 40-49: 27.03 %
  • 50-59: 8.11 %
  • 60+: 62.16 %

What are other drugs people take besides Hydrochlorothiazide? *

  1. Prilosec: 13 people, 28.89%
  2. Lisinopril: 11 people, 24.44%
  3. Humira: 9 people, 20.00%
  4. Sandostatin Lar: 9 people, 20.00%
  5. Synthroid: 7 people, 15.56%
  6. Amlodipine: 7 people, 15.56%
  7. Fosamax: 7 people, 15.56%
  8. Clonidine: 6 people, 13.33%
  9. Plavix: 6 people, 13.33%
  10. Ultram: 6 people, 13.33%

What are other side effects people have besides Biliary tract disorder? *

  1. Diarrhea: 23 people, 51.11%
  2. Nausea (feeling of having an urge to vomit): 19 people, 42.22%
  3. Abdominal Pain: 17 people, 37.78%
  4. Hepatic Failure (liver failure): 13 people, 28.89%
  5. Cholangitis (infection of the bile duct): 13 people, 28.89%
  6. Abdominal Distension: 13 people, 28.89%
  7. Fall: 12 people, 26.67%
  8. Acute Kidney Failure: 12 people, 26.67%
  9. Bile Duct Stenosis (abnormal narrowing of the common bile duct): 11 people, 24.44%
  10. Hepatomegaly (abnormal enlargement of the liver): 11 people, 24.44%

What are the existing conditions these people have? *

  1. Carcinoid Syndrome (syndrome includes flushing and diarrhoea, and, less frequently, heart failure and bronchoconstriction): 10 people, 22.22%
  2. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 7 people, 15.56%
  3. Pain: 5 people, 11.11%
  4. High Blood Cholesterol: 5 people, 11.11%
  5. Thyroid Diseases: 5 people, 11.11%
  6. Headache (pain in head): 5 people, 11.11%
  7. Immunodeficiency Common Variable: 4 people, 8.89%
  8. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 6.67%
  9. Type 2 Diabetes: 1 person, 2.22%
  10. Bipolar Disorder (mood disorder): 1 person, 2.22%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrochlorothiazide and have Biliary tract disorder?

- Check whether Biliary tract disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrochlorothiazide:

Biliary tract disorder treatments and more:

How severe was Biliary tract disorder and when was it recovered:

Expand to all the drugs that have ingredients of hydrochlorothiazide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Biliary tract disorder:

Browse all the conditions that are associated with Biliary tract disorder:


How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hydrochlorothiazide) and Hydrochlorothiazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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