Hydrochlorothiazide and Haemodynamic instability - a phase IV clinical study of FDA data

Summary:

Haemodynamic instability is reported as a side effect among people who take Hydrochlorothiazide (hydrochlorothiazide), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Amlodipine, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Haemodynamic instability when taking Hydrochlorothiazide. It is created by eHealthMe based on reports of 177,544 people who have side effects when taking Hydrochlorothiazide from the FDA, and is updated regularly.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

What is Haemodynamic instability?

Haemodynamic instability (disturbances in the blood movement in our body) is found to be associated with 550 drugs and 1,280 conditions by eHealthMe. Check the latest studies of Haemodynamic instability.

On Jul, 30, 2026

177,544 people reported to have side effects when taking Hydrochlorothiazide.
Among them, 98 people (0.06%) have Haemodynamic instability.

Could Hydrochlorothiazide cause Haemodynamic instability?

Among these 98 people:

How long have people been on Hydrochlorothiazide when they have Haemodynamic instability? *

What is the gender of people who have Haemodynamic instability when taking Hydrochlorothiazide? *

female: 34.83 %
male: 65.17 %

What is the age of people who have Haemodynamic instability when taking Hydrochlorothiazide? *

What are other drugs people take besides Hydrochlorothiazide? *

What are other side effects people have besides Haemodynamic instability? *

Hypotension (abnormally low blood pressure): 36 people, 36.73%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 23 people, 23.47%
Acute Kidney Failure: 20 people, 20.41%
Lactic Acidosis (low ph in body tissues): 20 people, 20.41%
Suicide Attempt: 14 people, 14.29%
Overdose: 14 people, 14.29%
Dyspnea (difficult or laboured breathing): 10 people, 10.20%
Nausea And Vomiting: 9 people, 9.18%
Consciousness - Decreased: 9 people, 9.18%
Pneumonia: 9 people, 9.18%

What are the existing conditions these people have? *

Type 2 Diabetes: 11 people, 11.22%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 6.12%
Anaesthesia: 5 people, 5.10%
Metastases To Lymph Nodes (cancer spreads to lymph node): 4 people, 4.08%
Dyslipidaemia (abnormal amount of lipids): 4 people, 4.08%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 4.08%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 3.06%
Overdose: 3 people, 3.06%
Diabetes: 3 people, 3.06%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 3.06%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrochlorothiazide and have Haemodynamic instability?

- Check whether Haemodynamic instability is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrochlorothiazide:

Hydrochlorothiazide (182,194 reports)

Browse all side effects of Hydrochlorothiazide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Haemodynamic instability:

Haemodynamic instability (550 drugs)

Browse all the conditions that are associated with Haemodynamic instability:

Haemodynamic instability (1,280 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hydrochlorothiazide) and Hydrochlorothiazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.