Hydrochlorothiazide and Thyroid function test abnormal - a phase IV clinical study of FDA data

Summary:

Thyroid function test abnormal is reported as a side effect among people who take Hydrochlorothiazide (hydrochlorothiazide), especially for people who are female, 60+ old, have been taking the drug for 5 - 10 years also take Synthroid, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Thyroid function test abnormal when taking Hydrochlorothiazide. It is created by eHealthMe based on reports of 177,544 people who have side effects when taking Hydrochlorothiazide from the FDA, and is updated regularly.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,169 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

What is Thyroid function test abnormal?

Thyroid function test abnormal is found to be associated with 1,714 drugs and 1,581 conditions by eHealthMe. Check the latest studies of Thyroid function test abnormal.

On Oct, 20, 2025

177,544 people reported to have side effects when taking Hydrochlorothiazide.
Among them, 435 people (0.25%) have Thyroid function test abnormal.

Could Hydrochlorothiazide cause Thyroid function test abnormal?

Among these 435 people:

How long have people been on Hydrochlorothiazide when they have Thyroid function test abnormal? *

What is the gender of people who have Thyroid function test abnormal when taking Hydrochlorothiazide? *

female: 80.63 %
male: 19.37 %

What is the age of people who have Thyroid function test abnormal when taking Hydrochlorothiazide? *

What are other drugs people take besides Hydrochlorothiazide? *

What are other side effects people have besides Thyroid function test abnormal? *

Pain: 131 people, 30.11%
Fatigue (feeling of tiredness): 102 people, 23.45%
Joint Pain: 89 people, 20.46%
Stress And Anxiety: 78 people, 17.93%
Diarrhea: 74 people, 17.01%
Dizziness: 73 people, 16.78%
Nausea (feeling of having an urge to vomit): 72 people, 16.55%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 72 people, 16.55%
Weight Decreased: 68 people, 15.63%
Dyspnea (difficult or laboured breathing): 64 people, 14.71%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 55 people, 12.64%
Multiple Myeloma (cancer of the plasma cells): 44 people, 10.11%
High Blood Cholesterol: 32 people, 7.36%
Depression: 29 people, 6.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 25 people, 5.75%
Pain: 23 people, 5.29%
Fibromyalgia (a long-term condition which causes pain all over the body): 22 people, 5.06%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 20 people, 4.60%
Stress And Anxiety: 20 people, 4.60%
Osteoporosis (bones weak and more likely to break): 20 people, 4.60%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrochlorothiazide and have Thyroid function test abnormal?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrochlorothiazide:

Hydrochlorothiazide (182,169 reports)

Browse all side effects of Hydrochlorothiazide:

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Common drugs associated with Thyroid function test abnormal:

Browse all the drugs that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,714 drugs)

Common conditions associated with Thyroid function test abnormal:

Rheumatoid arthritis aggravated: 1,901 reports
Ra: 1,897 reports
Ms: 1,590 reports
Htn: 1,297 reports
Thyroid disorder: 1,022 reports
Thyroid function test abnormal: 1,020 reports
Hypothyroidism: 1,006 reports
High blood cholesterol: 848 reports
Blood triglycerides increased: 844 reports
Lipoprotein test: 797 reports

Browse all the conditions that are associated with Thyroid function test abnormal:

Thyroid function test abnormal (1,581 conditions)

Drugs similar to Hydrochlorothiazide and Thyroid function test abnormal :

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide (the active ingredients of Hydrochlorothiazide) and Hydrochlorothiazide (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.