Hydrocodone and Laryngospasm - a phase IV clinical study of FDA data

Summary:

Laryngospasm is reported as a side effect among people who take Hydrocodone (hydrocodone bitartrate; ibuprofen), especially for people who are male, 20-29 old, also take Acetaminophen, and have Acute hepatic failure.

The phase IV clinical study analyzes which people have Laryngospasm when taking Hydrocodone. It is created by eHealthMe based on reports of 13,053 people who have side effects when taking Hydrocodone from the FDA, and is updated regularly.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

What is Laryngospasm?

Laryngospasm (an uncontrolled/involuntary muscular contraction of larynx) is found to be associated with 365 drugs and 493 conditions by eHealthMe. Check the latest studies of Laryngospasm.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

13,053 people reported to have side effects when taking Hydrocodone.
Among them, 15 people (0.11%) have Laryngospasm.

Among these 15 people:

What is the gender of people who have Laryngospasm when taking Hydrocodone? *

female: 0.0 %
male: 100 %

What is the age of people who have Laryngospasm when taking Hydrocodone? *

What are other drugs people take besides Hydrocodone? *

Acetaminophen: 15 people, 100.00%
Naproxen: 14 people, 93.33%
Loratadine: 14 people, 93.33%
Ibuprofen: 14 people, 93.33%
Valtoco: 1 person, 6.67%
Triamcinolone Acetonide: 1 person, 6.67%
Onfi: 1 person, 6.67%
Nayzilam: 1 person, 6.67%
Klonopin: 1 person, 6.67%
Gabapentin: 1 person, 6.67%

What are other side effects people have besides Laryngospasm? *

Agitation (state of anxiety or nervous excitement): 14 people, 93.33%
Overdose: 13 people, 86.67%
Acute Hepatic Failure: 12 people, 80.00%
Bezoar (mass found trapped in the gastrointestinal system): 9 people, 60.00%
Analgesic Drug Level Increased: 4 people, 26.67%
International Normalised Ratio Increased: 2 people, 13.33%
Drug Ineffective: 1 person, 6.67%
Cerebral Palsy: 1 person, 6.67%
Constipation: 1 person, 6.67%
Transaminases Increased: 1 person, 6.67%

What are the existing conditions these people have? *

Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 6.67%
Acute Hepatic Failure: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocodone and have Laryngospasm?

- Check whether Laryngospasm is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocodone:

Hydrocodone (13,115 reports)

Laryngospasm treatments and more:

Laryngospasm (3,772 reports)

How severe was Laryngospasm and when was it recovered:

Laryngospasm in Hydrocodone

Expand to all the drugs that have ingredients of hydrocodone bitartrate; ibuprofen:

Laryngospasm and drugs with ingredients of hydrocodone bitartrate; ibuprofen

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Laryngospasm:

Laryngospasm (365 drugs)

Browse all the conditions that are associated with Laryngospasm:

Laryngospasm (493 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocodone bitartrate; ibuprofen (the active ingredients of Hydrocodone) and Hydrocodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.