Hydrocodone and Respiratory disorder - a phase IV clinical study of FDA data

Summary:

Respiratory disorder is reported as a side effect among people who take Hydrocodone (hydrocodone bitartrate; ibuprofen), especially for people who are female, 40-49 old, also take Lorazepam, and have Chronic lymphocytic leukaemia.

The phase IV clinical study analyzes which people have Respiratory disorder when taking Hydrocodone. It is created by eHealthMe based on reports of 13,053 people who have side effects when taking Hydrocodone from the FDA, and is updated regularly.

What is Hydrocodone?

Hydrocodone has active ingredients of hydrocodone bitartrate; ibuprofen. eHealthMe is studying from 13,115 Hydrocodone users. Check the latest studies of Hydrocodone.

What is Respiratory disorder?

Respiratory disorder (respiratory disease) is found to be associated with 1,534 drugs and 1,584 conditions by eHealthMe. Check the latest studies of Respiratory disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

13,053 people reported to have side effects when taking Hydrocodone.
Among them, 22 people (0.17%) have Respiratory disorder.

Could Hydrocodone cause Respiratory disorder?

Among these 22 people:

What is the gender of people who have Respiratory disorder when taking Hydrocodone? *

female: 60 %
male: 40 %

What is the age of people who have Respiratory disorder when taking Hydrocodone? *

What are other drugs people take besides Hydrocodone? *

What are other side effects people have besides Respiratory disorder? *

Urinary Tract Infection: 8 people, 36.36%
Weakness: 7 people, 31.82%
Rashes (redness): 7 people, 31.82%
Head Injury: 5 people, 22.73%
High Blood Pressure: 5 people, 22.73%
Fall: 4 people, 18.18%
Weight Increased: 4 people, 18.18%
Dizziness: 4 people, 18.18%
Dyspnea (difficult or laboured breathing): 4 people, 18.18%
Oropharyngeal Pain: 4 people, 18.18%

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 9.09%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
Immunodeficiency Common Variable: 2 people, 9.09%
Essential Thrombocythaemia (chronic blood cancer): 2 people, 9.09%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 2 people, 9.09%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 2 people, 9.09%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.55%
Renal Cell Carcinoma (a kidney cancer): 1 person, 4.55%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 4.55%
Psoriasis (immune-mediated disease that affects the skin): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocodone and have Respiratory disorder?

- Check whether Respiratory disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocodone:

Hydrocodone (13,115 reports)

Respiratory disorder treatments and more:

Respiratory disorder (39,758 reports)

How severe was Respiratory disorder and when was it recovered:

Respiratory disorder in Hydrocodone

Expand to all the drugs that have ingredients of hydrocodone bitartrate; ibuprofen:

Respiratory disorder and drugs with ingredients of hydrocodone bitartrate; ibuprofen (28 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Respiratory disorder:

Respiratory disorder (1,534 drugs)

Browse all the conditions that are associated with Respiratory disorder:

Respiratory disorder (1,584 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocodone bitartrate; ibuprofen (the active ingredients of Hydrocodone) and Hydrocodone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.