Hydrocortisone and Bruxism - a phase IV clinical study of FDA data

Summary:

Bruxism is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Premarin, and have Femur fracture.

The phase IV clinical study analyzes which people have Bruxism when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Bruxism?

Bruxism (habitual grinding of the teeth, typically during sleep) is found to be associated with 590 drugs and 983 conditions by eHealthMe. Check the latest studies of Bruxism.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 27, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 37 people (0.09%) have Bruxism.

Could Hydrocortisone cause Bruxism?

Among these 37 people:

How long have people been on Hydrocortisone when they have Bruxism? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Bruxism when taking Hydrocortisone? *

  • female: 62.5 %
  • male: 37.5 %

What is the age of people who have Bruxism when taking Hydrocortisone? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 32.26 %
  • 20-29: 0.0 %
  • 30-39: 3.23 %
  • 40-49: 3.23 %
  • 50-59: 16.13 %
  • 60+: 45.16 %

What are other drugs people take besides Hydrocortisone? *

  1. Premarin: 16 people, 43.24%
  2. Metolazone: 15 people, 40.54%
  3. Ambien: 15 people, 40.54%
  4. Famotidine: 15 people, 40.54%
  5. Ketoconazole: 15 people, 40.54%
  6. Gabapentin: 15 people, 40.54%
  7. Neurontin: 14 people, 37.84%
  8. Neupogen: 14 people, 37.84%
  9. Nabumetone: 14 people, 37.84%
  10. Mycostatin: 14 people, 37.84%

What are other side effects people have besides Bruxism? *

  1. Stress And Anxiety: 21 people, 56.76%
  2. Confusional State: 19 people, 51.35%
  3. Insomnia (sleeplessness): 18 people, 48.65%
  4. Peripheral Coldness: 18 people, 48.65%
  5. Pain: 18 people, 48.65%
  6. Fatigue (feeling of tiredness): 18 people, 48.65%
  7. Fall: 18 people, 48.65%
  8. Swallowing Difficulty: 17 people, 45.95%
  9. Gingival Bleeding (bleeding gums): 17 people, 45.95%
  10. Back Pain: 17 people, 45.95%

What are the existing conditions these people have? *

  1. Diabetes Insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function): 11 people, 29.73%
  2. Femur Fracture: 11 people, 29.73%
  3. Pain: 5 people, 13.51%
  4. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 10.81%
  5. Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration): 3 people, 8.11%
  6. Fracture Pain: 3 people, 8.11%
  7. Belching (release of gas from the digestive tract): 3 people, 8.11%
  8. Blood Sodium Abnormal: 3 people, 8.11%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 2.70%
  10. Type 2 Diabetes: 1 person, 2.70%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Bruxism?

- Check whether Bruxism is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Bruxism treatments and more:

How severe was Bruxism and when was it recovered:

Expand to all the drugs that have ingredients of hydrocortisone:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bruxism:

Browse all the conditions that are associated with Bruxism:


How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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