Hydrocortisone and Cardiac tamponade - a phase IV clinical study of FDA data

Summary:

Cardiac tamponade is reported as a side effect among people who take Hydrocortisone (hydrocortisone), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aranesp, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Cardiac tamponade when taking Hydrocortisone. It is created by eHealthMe based on reports of 39,960 people who have side effects when taking Hydrocortisone from the FDA, and is updated regularly.

What is Hydrocortisone?

Hydrocortisone has active ingredients of hydrocortisone. It is often used in addison's disease. eHealthMe is studying from 40,425 Hydrocortisone users. Check the latest studies of Hydrocortisone.

What is Cardiac tamponade?

Cardiac tamponade (fluid accumulates in heart covering) is found to be associated with 531 drugs and 774 conditions by eHealthMe. Check the latest studies of Cardiac tamponade.

On Jul, 15, 2026

39,960 people reported to have side effects when taking Hydrocortisone.
Among them, 30 people (0.08%) have Cardiac tamponade.

Could Hydrocortisone cause Cardiac tamponade?

Among these 30 people:

How long have people been on Hydrocortisone when they have Cardiac tamponade? *

What is the gender of people who have Cardiac tamponade when taking Hydrocortisone? *

female: 76.67 %
male: 23.33 %

What is the age of people who have Cardiac tamponade when taking Hydrocortisone? *

What are other drugs people take besides Hydrocortisone? *

Zometa: 7 people, 23.33%
Tetracycline Hydrochloride: 7 people, 23.33%
Cozaar: 7 people, 23.33%
Percocet: 7 people, 23.33%
Plaquenil: 7 people, 23.33%
Protonix: 7 people, 23.33%
Aricept: 7 people, 23.33%
Aredia: 7 people, 23.33%
Sodium Bicarbonate: 7 people, 23.33%
Aranesp: 7 people, 23.33%

What are other side effects people have besides Cardiac tamponade? *

Acute Kidney Failure: 14 people, 46.67%
Pericardial Effusion (fluid around the heart): 12 people, 40.00%
Pleural Effusion (water on the lungs): 11 people, 36.67%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 10 people, 33.33%
Cardiac Failure Congestive: 10 people, 33.33%
Hypotension (abnormally low blood pressure): 10 people, 33.33%
Mitral Valve Incompetence (inefficient heart valve): 9 people, 30.00%
Tricuspid Valve Incompetence (inefficient heart valve): 9 people, 30.00%
Pericarditis (inflammation of the pericardium): 9 people, 30.00%
General Physical Health Deterioration (weak health status): 8 people, 26.67%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 23.33%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 13.33%
Post Procedural Haemorrhage (post procedural bleeding): 4 people, 13.33%
Thrombocytopenia (decrease of platelets in blood): 2 people, 6.67%
Myocarditis (inflammation of heart muscle myocardium): 2 people, 6.67%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 2 people, 6.67%
Urinary Tract Infection: 1 person, 3.33%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 3.33%
Phantom Pain: 1 person, 3.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 3.33%

* Approximation only. Some reports may have incomplete information.

Do you take Hydrocortisone and have Cardiac tamponade?

- Check whether Cardiac tamponade is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Hydrocortisone:

Hydrocortisone (40,425 reports)

Browse all side effects of Hydrocortisone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiac tamponade:

Cardiac tamponade (531 drugs)

Browse all the conditions that are associated with Cardiac tamponade:

Cardiac tamponade (774 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on hydrocortisone (the active ingredients of Hydrocortisone) and Hydrocortisone (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.